{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["56(5)"],"submitter":["Hemrom A"],"pubmed_abstract":["<h4>Purpose</h4>Neuroblastoma (NB) is childhood's most common extracranial solid malignancy. We have compared two imaging modalities, <sup>131</sup>I-MIBG and <sup>18</sup>F-DOPA PET/CT, to evaluate NB. Also, feasibility of the application of standardised scoring systems, SIOPEN and Curie scoring systems, in <sup>18</sup>F-DOPA PET/CT was explored.<h4>Methods</h4>Patients with histopathology-proven NB underwent <sup>131</sup>I-MIBG (planar and SPECT/CT) and <sup>18</sup>F-DOPA PET/CT scans, as per standard imaging protocols. Duration between scans ranged from 1 to 30 days (median = 8 days). Number of lesions in Curie and SIOPEN scoring systems applied on both modalities was compared.<h4>Results</h4>Forty-six patients were included (M:F = 29:17) with a median age of 36 months. Both <sup>131"],"journal":["Nuclear medicine and molecular imaging"],"pagination":["236-244"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9508302"],"repository":["biostudies-literature"],"pubmed_title":["Comparative Role of <sup>18</sup>F-DOPA PET/CT and <sup>131</sup>I-MIBG Scintigraphy in Neuroblastoma and Application of Curie and SIOPEN Scoring Systems in <sup>18</sup>F-DOPA PET/CT."],"pmcid":["PMC9508302"],"pubmed_authors":["Hemrom A","Damle NA","Arora G","Bal C"],"additional_accession":[]},"is_claimable":false,"name":"Comparative Role of <sup>18</sup>F-DOPA PET/CT and <sup>131</sup>I-MIBG Scintigraphy in Neuroblastoma and Application of Curie and SIOPEN Scoring Systems in <sup>18</sup>F-DOPA PET/CT.","description":"<h4>Purpose</h4>Neuroblastoma (NB) is childhood's most common extracranial solid malignancy. We have compared two imaging modalities, <sup>131</sup>I-MIBG and <sup>18</sup>F-DOPA PET/CT, to evaluate NB. Also, feasibility of the application of standardised scoring systems, SIOPEN and Curie scoring systems, in <sup>18</sup>F-DOPA PET/CT was explored.<h4>Methods</h4>Patients with histopathology-proven NB underwent <sup>131</sup>I-MIBG (planar and SPECT/CT) and <sup>18</sup>F-DOPA PET/CT scans, as per standard imaging protocols. Duration between scans ranged from 1 to 30 days (median = 8 days). Number of lesions in Curie and SIOPEN scoring systems applied on both modalities was compared.<h4>Results</h4>Forty-six patients were included (M:F = 29:17) with a median age of 36 months. Both <sup>131","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-25T21:23:25.585Z","creation":"2025-04-06T08:45:50.19Z"},"accession":"S-EPMC9508302","cross_references":{"pubmed":["36310834"],"doi":["10.1007/s13139-022-00762-6"]}}