{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(5)"],"submitter":["Wang H"],"pubmed_abstract":["We comprehensively studied directional feedback and feedforward connectivity to explore potential connectivity changes that underlie propofol-induced deep sedation. We further investigated the corticocortical connectivity patterns within and between hemispheres. Sixty-channel electroencephalographic data were collected from 19 healthy volunteers in a resting wakefulness state and propofol-induced deep unconsciousness state defined by a bispectral index value of 40. A source analysis was employed to locate cortical activity. The Desikan-Killiany atlas was used to partition cortices, and directional functional connectivity was assessed by normalized symbolic transfer entropy between higher-order (prefrontal and frontal) and lower-order (auditory, sensorimotor and visual) cortices and between"],"journal":["Cognitive neurodynamics"],"pagination":["1029-1043"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9508318"],"repository":["biostudies-literature"],"pubmed_title":["Selective corticocortical connectivity suppression during propofol-induced anesthesia in healthy volunteers."],"pmcid":["PMC9508318"],"pubmed_authors":["Cai S","Wang Q","Zhang Y","Song D","Wang H","Huang L","Wang Y","Cheng H","Yan F"],"additional_accession":[]},"is_claimable":false,"name":"Selective corticocortical connectivity suppression during propofol-induced anesthesia in healthy volunteers.","description":"We comprehensively studied directional feedback and feedforward connectivity to explore potential connectivity changes that underlie propofol-induced deep sedation. We further investigated the corticocortical connectivity patterns within and between hemispheres. Sixty-channel electroencephalographic data were collected from 19 healthy volunteers in a resting wakefulness state and propofol-induced deep unconsciousness state defined by a bispectral index value of 40. A source analysis was employed to locate cortical activity. The Desikan-Killiany atlas was used to partition cortices, and directional functional connectivity was assessed by normalized symbolic transfer entropy between higher-order (prefrontal and frontal) and lower-order (auditory, sensorimotor and visual) cortices and between","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-05T09:42:40.04Z","creation":"2025-04-05T09:42:40.04Z"},"accession":"S-EPMC9508318","cross_references":{"pubmed":["36237410"],"doi":["10.1007/s11571-021-09775-x"]}}