{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Halloran CM"],"funding":["Cancer Research UK","National Institute for Health Research (NIHR)"],"pagination":["e198"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9508971"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["3(3)"],"pubmed_abstract":["Whether a Blumgart anastomosis (BA) is superior to Cattell-Warren anastomosis (CWA) in terms of postoperative pancreatic fistula (POPF) following pancreatoduodenectomy.<h4>Importance</h4>Complications driven by POPF following pancreatic cancer resection may hinder adjuvant therapy, shortening survival. BA may reduce complications compared to CWA, improving the use of adjuvant therapy and prolonging survival.<h4>Methods</h4>A multicenter double-blind, controlled trial of patients undergoing resection for suspected pancreatic head cancer, randomized during surgery to a BA or CWA, stratified by pancreatic consistency and duct diameter. The primary end point was POPF, and secondary outcome measures were adjuvant therapy use, specified surgical complications, quality of life, and survival from "],"journal":["Annals of surgery open : perspectives of surgical history, education, and clinical approaches"],"pubmed_title":["A Multicenter, Randomized, Double-Blinded, Clinical Trial Comparing Cattell-Warren and Blumgart Anastomoses Following Partial Pancreatoduodenectomy: PANasta Trial."],"pmcid":["PMC9508971"],"funding_grant_id":["16186","16791","17680","08/29/02","8968","11883","15957","16812","A16791"],"pubmed_authors":["Psarelli EE","Jackson R","Smith A","Halloran CM","Pausch TM","Gomez D","O'Reilly DA","Prachalias A","Reddy S","Neoptolemos JP","Davidson B","Platt K","Ghaneh P"],"additional_accession":[]},"is_claimable":false,"name":"A Multicenter, Randomized, Double-Blinded, Clinical Trial Comparing Cattell-Warren and Blumgart Anastomoses Following Partial Pancreatoduodenectomy: PANasta Trial.","description":"Whether a Blumgart anastomosis (BA) is superior to Cattell-Warren anastomosis (CWA) in terms of postoperative pancreatic fistula (POPF) following pancreatoduodenectomy.<h4>Importance</h4>Complications driven by POPF following pancreatic cancer resection may hinder adjuvant therapy, shortening survival. BA may reduce complications compared to CWA, improving the use of adjuvant therapy and prolonging survival.<h4>Methods</h4>A multicenter double-blind, controlled trial of patients undergoing resection for suspected pancreatic head cancer, randomized during surgery to a BA or CWA, stratified by pancreatic consistency and duct diameter. The primary end point was POPF, and secondary outcome measures were adjuvant therapy use, specified surgical complications, quality of life, and survival from ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2026-05-31T22:55:39.858Z","creation":"2024-11-15T00:40:35.275Z"},"accession":"S-EPMC9508971","cross_references":{"pubmed":["36199490"],"doi":["10.1097/AS9.0000000000000198"]}}