{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Piewbang C"],"funding":["Thailand Science Research and Innovation","The Second Century Fund (C2F), Chulalongkorn University","Ratchadapisek Somphot Fund for Postdoctoral Fellowship, Chulalongkorn University","National Research Council of Thailand","Thailand Research Fund","Joint Funding of External Research Project, Ratchadaphiseksomphot Endowment Fund and Veterinary Science Research Fund","Thailand Science Research and Innovation Fund (TSRI)"],"pagination":["1648-1659"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9511090"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["36(5)"],"pubmed_abstract":["<h4>Background</h4>Whether domestic cat hepadnavirus (DCH) infection is associated with clinical disease remains to be determined.<h4>Objectives</h4>To determine the relationship between DCH detection, hematology, serum bichemistry and liver histology in DCH-positive cats.<h4>Animals</h4>One thousand twenty-two cats in Thailand without concurrent diseases and not undergoing treatments adversely affecting the liver.<h4>Methods</h4>Retrospective cross-sectional study. Samples derived from cats with concurrent virus detection were excluded. DCH detection was determined in blood and fresh-frozen liver by quantitative polymerase chain reaction (qPCR) and further investigated in liver sections showing histological parenchymal disorders (HPD) and normal liver (HNL) using in situ hybridization (IS"],"journal":["Journal of veterinary internal medicine"],"pubmed_title":["Domestic cat hepadnavirus associated with hepatopathy in cats: A retrospective study."],"pmcid":["PMC9511090"],"funding_grant_id":["PHD/0021/256","NRCT5-RGJ63001-013","CU_FRB640001_01_31_2","NRCT5‐RGJ63001‐013","N42A650553","N41A640175","RES_65_005_31_005"],"pubmed_authors":["Piewbang C","Tummaruk P","Dankaona W","Yostawonkul J","Sirivisoot S","Poonsin P","Kasantikul T","Lacharoje S","Techangamsuwan S"],"additional_accession":[]},"is_claimable":false,"name":"Domestic cat hepadnavirus associated with hepatopathy in cats: A retrospective study.","description":"<h4>Background</h4>Whether domestic cat hepadnavirus (DCH) infection is associated with clinical disease remains to be determined.<h4>Objectives</h4>To determine the relationship between DCH detection, hematology, serum bichemistry and liver histology in DCH-positive cats.<h4>Animals</h4>One thousand twenty-two cats in Thailand without concurrent diseases and not undergoing treatments adversely affecting the liver.<h4>Methods</h4>Retrospective cross-sectional study. Samples derived from cats with concurrent virus detection were excluded. DCH detection was determined in blood and fresh-frozen liver by quantitative polymerase chain reaction (qPCR) and further investigated in liver sections showing histological parenchymal disorders (HPD) and normal liver (HNL) using in situ hybridization (IS","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2026-07-14T17:11:14.803Z","creation":"2025-02-19T01:21:30.295Z"},"accession":"S-EPMC9511090","cross_references":{"pubmed":["36054642"],"doi":["10.1111/jvim.16525"]}}