{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang K"],"funding":["National Key Research and Development Program of China"],"pagination":["e14043"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9511998"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10"],"pubmed_abstract":["<h4>Background</h4>The full-length 16S rRNA sequencing can better improve the taxonomic and phylogenetic resolution compared to the partial 16S rRNA gene sequencing. The 16S-FAS-NGS (16S rRNA full-length amplicon sequencing based on a next-generation sequencing platform) technology can generate high-quality, full-length 16S rRNA gene sequences using short-read sequencers, together with assembly procedures. However there is a lack of a data analysis suite that can help process and analyze the synthetic long read data.<h4>Results</h4>Herein, we developed software named 16S-FASAS (16S full-length amplicon sequencing data analysis software) for 16S-FAS-NGS data analysis, which provided high-fidelity species-level microbiome data. 16S-FASAS consists of data quality control, <i>de novo</i> assem"],"journal":["PeerJ"],"pubmed_title":["16S-FASAS: an integrated pipeline for synthetic full-length 16S rRNA gene sequencing data analysis."],"pmcid":["PMC9511998"],"funding_grant_id":["2020YFC2005406"],"pubmed_authors":["Lin R","Zhang K","Zhou Q","Zhang Z","Chang Y"],"additional_accession":[]},"is_claimable":false,"name":"16S-FASAS: an integrated pipeline for synthetic full-length 16S rRNA gene sequencing data analysis.","description":"<h4>Background</h4>The full-length 16S rRNA sequencing can better improve the taxonomic and phylogenetic resolution compared to the partial 16S rRNA gene sequencing. The 16S-FAS-NGS (16S rRNA full-length amplicon sequencing based on a next-generation sequencing platform) technology can generate high-quality, full-length 16S rRNA gene sequences using short-read sequencers, together with assembly procedures. However there is a lack of a data analysis suite that can help process and analyze the synthetic long read data.<h4>Results</h4>Herein, we developed software named 16S-FASAS (16S full-length amplicon sequencing data analysis software) for 16S-FAS-NGS data analysis, which provided high-fidelity species-level microbiome data. 16S-FASAS consists of data quality control, <i>de novo</i> assem","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-05-28T01:10:14.018Z","creation":"2025-04-19T22:49:08.342Z"},"accession":"S-EPMC9511998","cross_references":{"pubmed":["36172503"],"doi":["10.7717/peerj.14043"]}}