biostudies-literatureHiggins ETNCCIH NIH HHSNational Center for Complementary and Integrative Health100509https://www.ebi.ac.uk/biostudies/studies/S-EPMC9513112biostudies-literatureUnknown25<h4>Background</h4>Psychological distress and comorbid psychopathology contribute to exacerbation risk in patients with asthma. Thus, interventions designed to reduce stress and improve emotion regulation, such as Mindfulness-Based Stress Reduction (MBSR), may augment standard care. Few studies have addressed this question and a paucity of data exists to determine the ability of MBSR to impact clinical outcomes in asthma.<h4>Methods</h4>This randomized controlled trial investigated effects of MBSR training on asthma control and airway inflammation, in relation to psychological symptoms, in adults with asthma. Participants were randomized to an 8-week MBSR training (n = 35) or wait-list control group (n = 34). Clinically relevant asthma assessments, including Asthma Control Questionnaire anBrain, behavior, & immunity - healthClinically relevant effects of Mindfulness-Based Stress Reduction in individuals with asthma.PMC9513112P01AT004952P01 AT004952Higgins ETRosenkranz MAKlaus DRSachs JBusse WWBednarek GTDavidson RJGoldman RIfalseClinically relevant effects of Mindfulness-Based Stress Reduction in individuals with asthma.<h4>Background</h4>Psychological distress and comorbid psychopathology contribute to exacerbation risk in patients with asthma. Thus, interventions designed to reduce stress and improve emotion regulation, such as Mindfulness-Based Stress Reduction (MBSR), may augment standard care. Few studies have addressed this question and a paucity of data exists to determine the ability of MBSR to impact clinical outcomes in asthma.<h4>Methods</h4>This randomized controlled trial investigated effects of MBSR training on asthma control and airway inflammation, in relation to psychological symptoms, in adults with asthma. Participants were randomized to an 8-week MBSR training (n = 35) or wait-list control group (n = 34). Clinically relevant asthma assessments, including Asthma Control Questionnaire an2022-01-01T00:00:00Z2022 Nov2026-05-10T06:39:16.665Z2025-02-19T00:34:59.798ZS-EPMC95131123617730610.1016/j.bbih.2022.100509