{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Qiao Z"],"pubmed_abstract":["<h4>Background</h4><i>Sparassis latifolia</i> (<i>S. latifolia</i>) is a precious edible fungus with multiple biological activities. To date, no study has been investigated the underlying molecular mechanism of immunoregulation caused by the neutral polysaccharide of <i>S. latifolia.</i><h4>Materials and methods</h4>To investigate immunomodulatory mechanism of <i>S. latifolia</i> neutral polysaccharide (SLNP), SLNP was obtained from <i>S. latifolia</i> and its structure, immune receptors and regulation mechanism were studied.<h4>Results</h4><i>S. latifolia</i> neutral polysaccharide consisted of arabinose, galactose, glucose, xylose, and mannose with a molar ratio of 6:12:63:10:5. SLNP was a pyran polysaccharide with a relative molecular weight of 3.2 × 10<sup>5</sup> Da. SLNP promoted the"],"journal":["Frontiers in nutrition"],"pagination":["994971"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9515474"],"repository":["biostudies-literature"],"pubmed_title":["Effects of <i>Sparassis latifolia</i> neutral polysaccharide on immune activity <i>via</i> TLR4-mediated MyD88-dependent and independent signaling pathways in RAW264.7 macrophages."],"pmcid":["PMC9515474"],"pubmed_authors":["Wang M","Chang M","Cheng F","Cao J","Yun S","Qiao Z","Feng C","Zhao Y","Cheng Y"],"additional_accession":[]},"is_claimable":false,"name":"Effects of <i>Sparassis latifolia</i> neutral polysaccharide on immune activity <i>via</i> TLR4-mediated MyD88-dependent and independent signaling pathways in RAW264.7 macrophages.","description":"<h4>Background</h4><i>Sparassis latifolia</i> (<i>S. latifolia</i>) is a precious edible fungus with multiple biological activities. To date, no study has been investigated the underlying molecular mechanism of immunoregulation caused by the neutral polysaccharide of <i>S. latifolia.</i><h4>Materials and methods</h4>To investigate immunomodulatory mechanism of <i>S. latifolia</i> neutral polysaccharide (SLNP), SLNP was obtained from <i>S. latifolia</i> and its structure, immune receptors and regulation mechanism were studied.<h4>Results</h4><i>S. latifolia</i> neutral polysaccharide consisted of arabinose, galactose, glucose, xylose, and mannose with a molar ratio of 6:12:63:10:5. SLNP was a pyran polysaccharide with a relative molecular weight of 3.2 × 10<sup>5</sup> Da. SLNP promoted the","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-05-18T13:39:57.045Z","creation":"2024-10-18T22:47:56.407Z"},"accession":"S-EPMC9515474","cross_references":{"pubmed":["36185691"],"doi":["10.3389/fnut.2022.994971"]}}