biostudies-literatureUnknown9Yao B<h4>Background</h4> Spontaneous bilateral intraocular lens dislocation of the vitreous cavity is a rare ocular disorder. This article aims to comprehensively describe bilateral spontaneous intraocular lens dislocation with unilateral lamellar macular hole and retinoschisis in a Chinese woman with homocystinuria. <h4>Case presentation</h4> A 72-year-old Chinese woman with homocystinuria presented with a painless bilateral blurring of vision. The slit lamp showed the absence of lenses in both eyes. B-ultrasound and orbital computed tomography (CT) demonstrated bilateral posterior dislocation of the crystalline lenses, and spectral-domain optical coherence tomography (SD-OCT) revealed a lamellar macular hole and retinoschisis in the right eye. Biochemical examination demonstrated that the totFrontiers in cardiovascular medicinehttps://www.ebi.ac.uk/biostudies/studies/S-EPMC9515901biostudies-literatureCase report: Spontaneous bilateral intraocular lens dislocation in a patient with homocystinuriaPMC9515901Yao BChen XLiu GZhao XfalseCase report: Spontaneous bilateral intraocular lens dislocation in a patient with homocystinuria<h4>Background</h4> Spontaneous bilateral intraocular lens dislocation of the vitreous cavity is a rare ocular disorder. This article aims to comprehensively describe bilateral spontaneous intraocular lens dislocation with unilateral lamellar macular hole and retinoschisis in a Chinese woman with homocystinuria. <h4>Case presentation</h4> A 72-year-old Chinese woman with homocystinuria presented with a painless bilateral blurring of vision. The slit lamp showed the absence of lenses in both eyes. B-ultrasound and orbital computed tomography (CT) demonstrated bilateral posterior dislocation of the crystalline lenses, and spectral-domain optical coherence tomography (SD-OCT) revealed a lamellar macular hole and retinoschisis in the right eye. Biochemical examination demonstrated that the tot2022-01-01T00:00:00Z2022 Jan2025-04-22T06:17:11.708Z2025-02-19T00:34:49.738ZS-EPMC9515901