biostudies-literatureUnknown12(9)Heroux MEResearch must be well designed, properly conducted and clearly and transparently reported. Our independent medical research institute wanted a simple, generic tool to assess the quality of the research conducted by its researchers, with the goal of identifying areas that could be improved through targeted educational activities. Unfortunately, none was available, thus we devised our own. Here, we report development of the Quality Output Checklist and Content Assessment (QuOCCA), and its application to publications from our institute's scientists. Following consensus meetings and external review by statistical and methodological experts, 11 items were selected for the final version of the QuOCCA: research transparency (items 1-3), research design and analysis (items 4-6) and research reportBMJ opene060976https://www.ebi.ac.uk/biostudies/studies/S-EPMC9516158biostudies-literatureQuality Output Checklist and Content Assessment (QuOCCA): a new tool for assessing research quality and reproducibility.PMC9516158Green MAButler AAAffleck AJKiely KMMenant JCWewege MJones MGandevia SCHeroux MECashin AGvan Schooten KSCartwright AMcCaughey EJfalseQuality Output Checklist and Content Assessment (QuOCCA): a new tool for assessing research quality and reproducibility.Research must be well designed, properly conducted and clearly and transparently reported. Our independent medical research institute wanted a simple, generic tool to assess the quality of the research conducted by its researchers, with the goal of identifying areas that could be improved through targeted educational activities. Unfortunately, none was available, thus we devised our own. Here, we report development of the Quality Output Checklist and Content Assessment (QuOCCA), and its application to publications from our institute's scientists. Following consensus meetings and external review by statistical and methodological experts, 11 items were selected for the final version of the QuOCCA: research transparency (items 1-3), research design and analysis (items 4-6) and research report2022-01-01T00:00:00Z2022 Sep2025-04-19T05:18:58.231Z2025-04-19T05:18:58.231ZS-EPMC95161583616736910.1136/bmjopen-2022-060976