{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Winter A"],"funding":["Open Access Publication Fund of the University of Wuerzburg"],"pagination":["11709"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9517310"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(18)"],"pubmed_abstract":["Medication-related osteonecrosis of the jaw (MRONJ) represents an adverse side effect of antiresorptive and antiangiogenic medications. It is associated with impaired quality of life, oral health, and oral function and can be classified into various stages. The purpose of this prospective clinical study is to evaluate the impact of stages I and II MRONJ on oral-health-related quality of life (OHRQoL) and related parameters. Patients' OHRQoL, satisfaction with life, oral discomfort, and oral health were assessed using the German version of the Oral Health Impact Profile (OHIP-G49), visual analog scales (VAS), and Satisfaction with Life Scale (SWLS) at baseline (T0), 10 days (T1), and 3 months after treatment (T2) in 36 patients. Data were analyzed using Kolmogorov-Smirnov test, two-way mixe"],"journal":["International journal of environmental research and public health"],"pubmed_title":["Oral-Health-Related Quality of Life in Patients with Medication-Related Osteonecrosis of the Jaw: A Prospective Clinical Study."],"pmcid":["PMC9517310"],"funding_grant_id":["n.a."],"pubmed_authors":["Schulz SM","Schmitter M","Straub A","Brands RC","Borgmann A","Hartmann S","Winter A","Kubler A"],"additional_accession":[]},"is_claimable":false,"name":"Oral-Health-Related Quality of Life in Patients with Medication-Related Osteonecrosis of the Jaw: A Prospective Clinical Study.","description":"Medication-related osteonecrosis of the jaw (MRONJ) represents an adverse side effect of antiresorptive and antiangiogenic medications. It is associated with impaired quality of life, oral health, and oral function and can be classified into various stages. The purpose of this prospective clinical study is to evaluate the impact of stages I and II MRONJ on oral-health-related quality of life (OHRQoL) and related parameters. Patients' OHRQoL, satisfaction with life, oral discomfort, and oral health were assessed using the German version of the Oral Health Impact Profile (OHIP-G49), visual analog scales (VAS), and Satisfaction with Life Scale (SWLS) at baseline (T0), 10 days (T1), and 3 months after treatment (T2) in 36 patients. Data were analyzed using Kolmogorov-Smirnov test, two-way mixe","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-19T05:18:21.543Z","creation":"2025-04-19T05:18:21.543Z"},"accession":"S-EPMC9517310","cross_references":{"pubmed":["36141982"],"doi":["10.3390/ijerph191811709"]}}