{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(43)"],"submitter":["Yang K"],"pubmed_abstract":["Synthetic ionophores are promising therapeutic targets, yet poor water solubility limits their potential for translation into the clinic. Here we report a water-soluble, supramolecular self-associating amphiphile that functions as a cation uniporter in synthetic vesicle systems, deriving mechanistic insight through planar bilayer patch clamp experiments."],"journal":["RSC advances"],"pagination":["27877-27880"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9520675"],"repository":["biostudies-literature"],"pubmed_title":["A water-soluble membrane transporter for biologically relevant cations."],"pmcid":["PMC9520675"],"pubmed_authors":["Yang K","Long Y","Hiscock JR","Haynes CJE","White LJ","Lai HY","Boles JE","Hilton KLF"],"additional_accession":[]},"is_claimable":false,"name":"A water-soluble membrane transporter for biologically relevant cations.","description":"Synthetic ionophores are promising therapeutic targets, yet poor water solubility limits their potential for translation into the clinic. Here we report a water-soluble, supramolecular self-associating amphiphile that functions as a cation uniporter in synthetic vesicle systems, deriving mechanistic insight through planar bilayer patch clamp experiments.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-05T13:27:47.454Z","creation":"2025-02-19T01:30:46.519Z"},"accession":"S-EPMC9520675","cross_references":{"pubmed":["36320246"],"doi":["10.1039/d2ra05314d"]}}