biostudies-literatureUnknown17(9)Powell A<h4>Background</h4>Alcohol use disorders (AUD) associate with structural and functional brain differences, including impairments in neuropsychological functions; however, review level research (largely cross-sectional) is inconsistent with regards to recovery of such functions following abstinence. Such recovery is important, as these impairments associate with treatment outcomes and quality of life.<h4>Objective(s)</h4>To assess neuropsychological function recovery following abstinence in individuals with a clinical AUD diagnosis. The secondary objective is to assess predictors of neuropsychological recovery in AUD.<h4>Methods</h4>Four electronic databases (APA PsycInfo, EBSCO MEDLINE, CINAHL, Web of Science Core Collection) will be searched between 1999-2022, with search strategies adaptPloS onee0274752https://www.ebi.ac.uk/biostudies/studies/S-EPMC9521940biostudies-literatureRecovery of neuropsychological function following abstinence from alcohol in adults diagnosed with an alcohol use disorder: Protocol for a systematic review of longitudinal studies.PMC9521940Kuiper RSumnall HMontgomery CPowell ASmith JfalseRecovery of neuropsychological function following abstinence from alcohol in adults diagnosed with an alcohol use disorder: Protocol for a systematic review of longitudinal studies.<h4>Background</h4>Alcohol use disorders (AUD) associate with structural and functional brain differences, including impairments in neuropsychological functions; however, review level research (largely cross-sectional) is inconsistent with regards to recovery of such functions following abstinence. Such recovery is important, as these impairments associate with treatment outcomes and quality of life.<h4>Objective(s)</h4>To assess neuropsychological function recovery following abstinence in individuals with a clinical AUD diagnosis. The secondary objective is to assess predictors of neuropsychological recovery in AUD.<h4>Methods</h4>Four electronic databases (APA PsycInfo, EBSCO MEDLINE, CINAHL, Web of Science Core Collection) will be searched between 1999-2022, with search strategies adapt2022-01-01T00:00:00Z20222025-07-25T03:08:05.07Z2025-04-21T14:34:59.393ZS-EPMC95219403617397610.1371/journal.pone.0274752