{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang L"],"funding":["National Natural Science Foundation of China","Sanming Project of Medicine in Shenzhen"],"pagination":["455-467"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9524311"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["187(5-6)"],"pubmed_abstract":["<h4>Purpose</h4>Talaromyces marneffei (TM) is an opportunistic fungus leading to multi-organ damages and poor prognosis in immunocompromised individuals. TM infections in children are rare and our knowledge to TM infection is insufficient. To investigate the clinical characteristics of TM-infected children and to explore the underlying mechanisms for host against TM, we analysed TM-infected patients diagnosed in our hospital.<h4>Methods</h4>Eight patients with TM infections have been identified in Shenzhen Children's Hospital during 2017-2021. Clinical data were collected from medical records. Immunological features were evaluated by flow cytometry. Literatures were also reviewed to summarize the reported inborn errors of immunity (IEIs) with TM infections.<h4>Results</h4>All 8 children we"],"journal":["Mycopathologia"],"pubmed_title":["Talaromyces marneffei Infections in 8 Chinese Children with Inborn Errors of Immunity."],"pmcid":["PMC9524311"],"funding_grant_id":["SZSM201812002","81900638"],"pubmed_authors":["Xia Y","Weng R","Yang J","Ling J","Wang L","Li X","Li Y","Yang Z","He T","Huang Y","Qi Z","Luo Y","Zhu X","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"Talaromyces marneffei Infections in 8 Chinese Children with Inborn Errors of Immunity.","description":"<h4>Purpose</h4>Talaromyces marneffei (TM) is an opportunistic fungus leading to multi-organ damages and poor prognosis in immunocompromised individuals. TM infections in children are rare and our knowledge to TM infection is insufficient. To investigate the clinical characteristics of TM-infected children and to explore the underlying mechanisms for host against TM, we analysed TM-infected patients diagnosed in our hospital.<h4>Methods</h4>Eight patients with TM infections have been identified in Shenzhen Children's Hospital during 2017-2021. Clinical data were collected from medical records. Immunological features were evaluated by flow cytometry. Literatures were also reviewed to summarize the reported inborn errors of immunity (IEIs) with TM infections.<h4>Results</h4>All 8 children we","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-03T21:30:38.607Z","creation":"2025-04-03T21:30:38.607Z"},"accession":"S-EPMC9524311","cross_references":{"pubmed":["36180657"],"doi":["10.1007/s11046-022-00659-0"]}}