biostudies-literatureWang LNational Natural Science Foundation of ChinaSanming Project of Medicine in Shenzhen455-467https://www.ebi.ac.uk/biostudies/studies/S-EPMC9524311biostudies-literatureUnknown187(5-6)<h4>Purpose</h4>Talaromyces marneffei (TM) is an opportunistic fungus leading to multi-organ damages and poor prognosis in immunocompromised individuals. TM infections in children are rare and our knowledge to TM infection is insufficient. To investigate the clinical characteristics of TM-infected children and to explore the underlying mechanisms for host against TM, we analysed TM-infected patients diagnosed in our hospital.<h4>Methods</h4>Eight patients with TM infections have been identified in Shenzhen Children's Hospital during 2017-2021. Clinical data were collected from medical records. Immunological features were evaluated by flow cytometry. Literatures were also reviewed to summarize the reported inborn errors of immunity (IEIs) with TM infections.<h4>Results</h4>All 8 children weMycopathologiaTalaromyces marneffei Infections in 8 Chinese Children with Inborn Errors of Immunity.PMC9524311SZSM20181200281900638Xia YWeng RYang JLing JWang LLi XLi YYang ZHe THuang YQi ZLuo YZhu XXu YfalseTalaromyces marneffei Infections in 8 Chinese Children with Inborn Errors of Immunity.<h4>Purpose</h4>Talaromyces marneffei (TM) is an opportunistic fungus leading to multi-organ damages and poor prognosis in immunocompromised individuals. TM infections in children are rare and our knowledge to TM infection is insufficient. To investigate the clinical characteristics of TM-infected children and to explore the underlying mechanisms for host against TM, we analysed TM-infected patients diagnosed in our hospital.<h4>Methods</h4>Eight patients with TM infections have been identified in Shenzhen Children's Hospital during 2017-2021. Clinical data were collected from medical records. Immunological features were evaluated by flow cytometry. Literatures were also reviewed to summarize the reported inborn errors of immunity (IEIs) with TM infections.<h4>Results</h4>All 8 children we2022-01-01T00:00:00Z2022 Dec2025-04-03T21:30:38.607Z2025-04-03T21:30:38.607ZS-EPMC95243113618065710.1007/s11046-022-00659-0