{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(42)"],"submitter":["Hricovini M"],"pubmed_abstract":["High-resolution NMR experiments revealed that differently substituted quinazolinone-based Schiff bases undergo <i>anti</i> to <i>syn</i> isomerisation on exposure to ultraviolet light in DMSO solution. The degree <i>anti</i> to <i>syn</i> conversion varied significantly upon substitution (between 5% and 100%) and also showed two noteworthy features: that relaxation back to the <i>anti</i>-form goes far faster (by at least 3 orders of magnitude) when the C<sub>6</sub> rings B and C have <i>ortho</i>-OH substituents, and that relaxation can also be significantly sped up by addition of acid. Two possible mechanisms explaining the differences in relaxation process have been proposed: (I) the interaction of the azomethine hydrogen with the carbonyl oxygen results in slower reversion to the <i>a"],"journal":["RSC advances"],"pagination":["27442-27452"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9524441"],"repository":["biostudies-literature"],"pubmed_title":["A study of the photochemical behaviour and relaxation mechanisms of <i>anti</i>-<i>syn</i> isomerisation around quinazolinone -N-N[double bond, length as m-dash] bonds."],"pmcid":["PMC9524441"],"pubmed_authors":["Hricovini M","Asher JR"],"additional_accession":[]},"is_claimable":false,"name":"A study of the photochemical behaviour and relaxation mechanisms of <i>anti</i>-<i>syn</i> isomerisation around quinazolinone -N-N[double bond, length as m-dash] bonds.","description":"High-resolution NMR experiments revealed that differently substituted quinazolinone-based Schiff bases undergo <i>anti</i> to <i>syn</i> isomerisation on exposure to ultraviolet light in DMSO solution. The degree <i>anti</i> to <i>syn</i> conversion varied significantly upon substitution (between 5% and 100%) and also showed two noteworthy features: that relaxation back to the <i>anti</i>-form goes far faster (by at least 3 orders of magnitude) when the C<sub>6</sub> rings B and C have <i>ortho</i>-OH substituents, and that relaxation can also be significantly sped up by addition of acid. Two possible mechanisms explaining the differences in relaxation process have been proposed: (I) the interaction of the azomethine hydrogen with the carbonyl oxygen results in slower reversion to the <i>a","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-05T13:27:38.748Z","creation":"2025-04-05T13:27:38.748Z"},"accession":"S-EPMC9524441","cross_references":{"pubmed":["36321162"],"doi":["10.1039/d2ra04529j"]}}