biostudies-literatureUnknown26(5)Timmer AS<h4>Objective</h4>To assess mesh behaviour and clinical outcomes of open complex abdominal wall reconstruction (CAWR) with the use of a polypropylene reinforced tissue matrix.<h4>Methods</h4>A multicenter retrospective study of adult patients who underwent open CAWR with the use of a permanent polypropylene reinforced tissue matrix (OviTex^®) between June 2019 and January 2021.<h4>Results</h4>Fifty-five consecutive patients from four hospitals in the Netherlands were analysed; 46 patients with a ventral hernia and 9 patients with an open abdomen. Most patients with a ventral hernia had one or more complicating comorbidities (91.3%) and one or more complicating hernia characteristics (95.7%). Most procedures were performed in a (clean) contaminated surgical field (69.6% CDC 2-4; 4Hernia : the journal of hernias and abdominal wall surgery1241-1250https://www.ebi.ac.uk/biostudies/studies/S-EPMC9525385biostudies-literatureClinical outcomes of open abdominal wall reconstruction with the use of a polypropylene reinforced tissue matrix: a multicenter retrospective study.PMC9525385Verdaasdonk EGGSchreurs WHHaenen SMDraaisma WABastiaansen AJNMWolffenbuttel CPTimmer ASBelt EJTBoermeester MAClaessen JJMBrouwer de Koning IMfalseClinical outcomes of open abdominal wall reconstruction with the use of a polypropylene reinforced tissue matrix: a multicenter retrospective study.<h4>Objective</h4>To assess mesh behaviour and clinical outcomes of open complex abdominal wall reconstruction (CAWR) with the use of a polypropylene reinforced tissue matrix.<h4>Methods</h4>A multicenter retrospective study of adult patients who underwent open CAWR with the use of a permanent polypropylene reinforced tissue matrix (OviTex^®) between June 2019 and January 2021.<h4>Results</h4>Fifty-five consecutive patients from four hospitals in the Netherlands were analysed; 46 patients with a ventral hernia and 9 patients with an open abdomen. Most patients with a ventral hernia had one or more complicating comorbidities (91.3%) and one or more complicating hernia characteristics (95.7%). Most procedures were performed in a (clean) contaminated surgical field (69.6% CDC 2-4; 42022-01-01T00:00:00Z2022 Oct2025-04-22T03:40:20.506Z2025-02-19T00:24:11.646ZS-EPMC95253853544128410.1007/s10029-022-02604-y