{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang X"],"funding":["Dongmei Diao"],"pagination":["16432"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9525585"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(1)"],"pubmed_abstract":["As a marker of hypercoagulability, plasma D-dimer is associated with progression of many cancers but remains controversial in gastric cancer (GC). We aim to investigate the predictive value of D-dimer for postoperative outcomes after radical gastrectomy of GC patients. We enrolled 903 consecutive patients with GC who underwent radical gastrectomy and the clinicopathological characteristics were compared. Risk factors for overall survival (OS) and disease-free survival (DFS) were determined using multivariate cox regression analysis. We also compared the survival difference based on Kaplan-Meier method after a one-to-one propensity score matching (PSM). Patients with elevated D-dimer had older age (p < 0.001), advanced TNM stage (p < 0.001), larger tumor size (p = 0.005), lower 5-year OS ra"],"journal":["Scientific reports"],"pubmed_title":["D-dimer, a predictor of bad outcome in gastric cancer patients undergoing radical resection."],"pmcid":["PMC9525585"],"funding_grant_id":["the National Natural Science Foundation of China (NO.81501826), the National Natural Science Foundation of Shaanxi (2020JQ-504;2020JQ540, 2021JM256), clinical cancer research center of Shaanxi Province (2019LCZX-02) and Science Foundation of Xi’an (20YXYJ0002(2))."],"pubmed_authors":["Li W","Zhang X","Sun T","Diao D","Dang C","Wang X"],"additional_accession":[]},"is_claimable":false,"name":"D-dimer, a predictor of bad outcome in gastric cancer patients undergoing radical resection.","description":"As a marker of hypercoagulability, plasma D-dimer is associated with progression of many cancers but remains controversial in gastric cancer (GC). We aim to investigate the predictive value of D-dimer for postoperative outcomes after radical gastrectomy of GC patients. We enrolled 903 consecutive patients with GC who underwent radical gastrectomy and the clinicopathological characteristics were compared. Risk factors for overall survival (OS) and disease-free survival (DFS) were determined using multivariate cox regression analysis. We also compared the survival difference based on Kaplan-Meier method after a one-to-one propensity score matching (PSM). Patients with elevated D-dimer had older age (p < 0.001), advanced TNM stage (p < 0.001), larger tumor size (p = 0.005), lower 5-year OS ra","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-26T11:59:35.616Z","creation":"2025-04-06T13:50:23.123Z"},"accession":"S-EPMC9525585","cross_references":{"pubmed":["36180481"],"doi":["10.1038/s41598-022-16582-9"]}}