{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lee YB"],"funding":["Ministry of Trade, Industry and Energy","Ministry of Education","Ministry of Science and ICT","Ministry of Food and Drug Safety","Korea Medical Device Development Fund","Korea Health Industry Development Institute","Ministry of Health and Welfare","National Research Foundation of Korea"],"pagination":["722-732"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9532170"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["46(5)"],"pubmed_abstract":["<h4>Background</h4>We assessed the myocardial infarction (MI), stroke, and all-cause death risks during follow-up according to the low-density lipoprotein cholesterol (LDL-C) levels among older adults.<h4>Methods</h4>The Korean National Health Insurance Service datasets (2002 to 2020) were used for this population-based cohort study. The hazards of MI, stroke, and all-cause mortality during follow-up were analyzed according to LDL-C level in individuals aged ≥65 years without baseline cardiovascular diseases (n=1,391,616).<h4>Results</h4>During a mean 7.55 years, 52,753 MIs developed; 84,224 strokes occurred over a mean 7.47 years. After a mean 8.50 years, 233,963 died. A decrease in LDL-C was associated with lower hazards of MI and stroke. The decreased hazard of stroke in lower LDL-C was"],"journal":["Diabetes & metabolism journal"],"pubmed_title":["Myocardial Infarction, Stroke, and All-Cause Mortality according to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study."],"pmcid":["PMC9532170"],"funding_grant_id":["KMDF_PR_20200901_0233","9991007469, KMDF_PR_20200901_0233","R2106541","9991007469","HR20C0021"],"pubmed_authors":["Lee YB","Noh E","Hwang SY","Choi KM","Roh E","Yoo HJ","Cho GJ","Koo M","Kim JA","Hong SH","Baik SH"],"additional_accession":[]},"is_claimable":false,"name":"Myocardial Infarction, Stroke, and All-Cause Mortality according to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study.","description":"<h4>Background</h4>We assessed the myocardial infarction (MI), stroke, and all-cause death risks during follow-up according to the low-density lipoprotein cholesterol (LDL-C) levels among older adults.<h4>Methods</h4>The Korean National Health Insurance Service datasets (2002 to 2020) were used for this population-based cohort study. The hazards of MI, stroke, and all-cause mortality during follow-up were analyzed according to LDL-C level in individuals aged ≥65 years without baseline cardiovascular diseases (n=1,391,616).<h4>Results</h4>During a mean 7.55 years, 52,753 MIs developed; 84,224 strokes occurred over a mean 7.47 years. After a mean 8.50 years, 233,963 died. A decrease in LDL-C was associated with lower hazards of MI and stroke. The decreased hazard of stroke in lower LDL-C was","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-05T11:37:49.562Z","creation":"2025-04-05T11:37:49.562Z"},"accession":"S-EPMC9532170","cross_references":{"pubmed":["35255552"],"doi":["10.4093/dmj.2021.0225"]}}