{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(5)"],"submitter":["Farrell SW"],"pubmed_abstract":["<h4>Background</h4>We examined the associations of cardiorespiratory fitness (CRF) and white blood cell count (WBC) with mortality outcomes.<h4>Methods</h4>A total of 52,056 apparently healthy adults completed a comprehensive health examination, including a maximal treadmill test and blood chemistry analyses. CRF was categorized as high, moderate, or low by age and sex; WBC was categorized as sex-specific quartiles.<h4>Results</h4>During 17.8 ± 9.5 years (mean ± SD) of follow-up, a total of 4088 deaths occurred. When regressed jointly, significantly decreased all-cause mortality across CRF categories was observed within each quartile of WBC in men. Within WBC Quartile 1, all-cause mortality hazard ratios (HRs) with a 95% confidence interval (95%CI) were 1.0 (referent), 1.29 (95%CI: 1.06‒1."],"journal":["Journal of sport and health science"],"pagination":["605-612"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9532609"],"repository":["biostudies-literature"],"pubmed_title":["Cardiorespiratory fitness, white blood cell count, and mortality in men and women."],"pmcid":["PMC9532609"],"pubmed_authors":["Shuval K","Leonard D","Haskell WL","Farrell SW","Barlow CE","DeFina LF","Pavlovic A"],"additional_accession":[]},"is_claimable":false,"name":"Cardiorespiratory fitness, white blood cell count, and mortality in men and women.","description":"<h4>Background</h4>We examined the associations of cardiorespiratory fitness (CRF) and white blood cell count (WBC) with mortality outcomes.<h4>Methods</h4>A total of 52,056 apparently healthy adults completed a comprehensive health examination, including a maximal treadmill test and blood chemistry analyses. CRF was categorized as high, moderate, or low by age and sex; WBC was categorized as sex-specific quartiles.<h4>Results</h4>During 17.8 ± 9.5 years (mean ± SD) of follow-up, a total of 4088 deaths occurred. When regressed jointly, significantly decreased all-cause mortality across CRF categories was observed within each quartile of WBC in men. Within WBC Quartile 1, all-cause mortality hazard ratios (HRs) with a 95% confidence interval (95%CI) were 1.0 (referent), 1.29 (95%CI: 1.06‒1.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-21T16:50:14.18Z","creation":"2025-04-05T11:38:14.213Z"},"accession":"S-EPMC9532609","cross_references":{"pubmed":["34740872"],"doi":["10.1016/j.jshs.2021.10.005"]}}