{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["35(5)"],"submitter":["Amjadian S"],"pubmed_abstract":["<h4>Background</h4>Wound healing is a complex process including hemostasis, inflammation, proliferation, and remodeling during which an orchestrated array of biological and molecular events occurs to promote skin regeneration. Abnormalities in each step of the wound healing process lead to reparative rather than regenerative responses, thereby driving the formation of cutaneous scar. Patients suffering from scars represent serious health problems such as contractures, functional and esthetic concerns as well as painful, thick, and itchy complications, which generally decrease the quality of life and impose high medical costs. Therefore, therapies reducing cutaneous scarring are necessary to improve patients' rehabilitation.<h4>Summary</h4>Current approaches to remove scars, including surgi"],"journal":["Skin pharmacology and physiology"],"pagination":["247-265"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9533440"],"repository":["biostudies-literature"],"pubmed_title":["The Emerging Therapeutic Targets for Scar Management: Genetic and Epigenetic Landscapes."],"pmcid":["PMC9533440"],"pubmed_authors":["Amjadian S","Moradi S","Mohammadi P"],"additional_accession":[]},"is_claimable":false,"name":"The Emerging Therapeutic Targets for Scar Management: Genetic and Epigenetic Landscapes.","description":"<h4>Background</h4>Wound healing is a complex process including hemostasis, inflammation, proliferation, and remodeling during which an orchestrated array of biological and molecular events occurs to promote skin regeneration. Abnormalities in each step of the wound healing process lead to reparative rather than regenerative responses, thereby driving the formation of cutaneous scar. Patients suffering from scars represent serious health problems such as contractures, functional and esthetic concerns as well as painful, thick, and itchy complications, which generally decrease the quality of life and impose high medical costs. Therefore, therapies reducing cutaneous scarring are necessary to improve patients' rehabilitation.<h4>Summary</h4>Current approaches to remove scars, including surgi","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-22T21:52:42.964Z","creation":"2025-02-19T01:28:13.51Z"},"accession":"S-EPMC9533440","cross_references":{"pubmed":["35696989"],"doi":["10.1159/000524990"]}}