{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["276(5)"],"submitter":["Asnong A"],"pubmed_abstract":["<h4>Background and objective</h4>Total mesorectal excision (TME) for rectal cancer (RC) often results in significant bowel symptoms, commonly known as low anterior resection syndrome (LARS). Although pelvic floor muscle training (PFMT) is recommended in noncancer populations for treating bowel symptoms, this has been scarcely investigated in RC patients. The objective was to investigate PFMT effectiveness on LARS in patients after TME for RC.<h4>Methods</h4>A multicenter, single-blind prospective randomized controlled trial comparing PFMT (intervention; n=50) versus no PFMT (control; n=54) 1 month following TME/stoma closure was performed. The primary endpoint was the proportion of participants with an improvement in the LARS category at 4 months. Secondary outcomes were: continuous LARS s"],"journal":["Annals of surgery"],"pagination":["761-768"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9534049"],"repository":["biostudies-literature"],"pubmed_title":["The Role of Pelvic Floor Muscle Training on Low Anterior Resection Syndrome: A Multicenter Randomized Controlled Trial."],"pmcid":["PMC9534049"],"pubmed_authors":["Asnong A","De Groef A","Devoogdt N","Guler Caamano Fajardo I","Geraerts I","Wolthuis A","Van Molhem Y","Van Geluwe B","Van Kampen M","D'Hoore A"],"additional_accession":[]},"is_claimable":false,"name":"The Role of Pelvic Floor Muscle Training on Low Anterior Resection Syndrome: A Multicenter Randomized Controlled Trial.","description":"<h4>Background and objective</h4>Total mesorectal excision (TME) for rectal cancer (RC) often results in significant bowel symptoms, commonly known as low anterior resection syndrome (LARS). Although pelvic floor muscle training (PFMT) is recommended in noncancer populations for treating bowel symptoms, this has been scarcely investigated in RC patients. The objective was to investigate PFMT effectiveness on LARS in patients after TME for RC.<h4>Methods</h4>A multicenter, single-blind prospective randomized controlled trial comparing PFMT (intervention; n=50) versus no PFMT (control; n=54) 1 month following TME/stoma closure was performed. The primary endpoint was the proportion of participants with an improvement in the LARS category at 4 months. Secondary outcomes were: continuous LARS s","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-05T11:38:29.092Z","creation":"2025-04-05T11:38:29.092Z"},"accession":"S-EPMC9534049","cross_references":{"pubmed":["35894434"],"doi":["10.1097/SLA.0000000000005632"]}}