biostudies-literatureUnknown78(Pt 10)Naeem MThe solid-state structures of two solvated forms of 4-glutarato-<i>N</i>,<i>N</i>-diiso-propyl-tryptamine were determined by single-crystal X-ray diffraction, namely, 5-[(3-{2-[bis(propan-2-yl)azaniumyl]ethyl}-1<i>H</i>-indol-4-yl)oxy]-5-oxopentanoate meth-anol monosolvate, C₂₁H₃₀N₂O₄·CH₃OH, and the analogous ethanol monosolvate, C₂₁H₃₀N₂O₄·C₂H₆O. In both compounds, the 4-glutarato-<i>N</i>,<i>N</i>-di-iso--pro-pyl-tryptamine exists as a zwitterion with a protonated tertiary ammonium and a deprotonated glutarato carboxyl-ate. The tryptamine zwitterions and alcohol solvates in both structures combine to produce near identical hydrogen-bonding networks, with N-H⋯O and O-H⋯Acta crystallographica. Section E, Crystallographic communications1034-1038https://www.ebi.ac.uk/biostudies/studies/S-EPMC9535823biostudies-literatureThe methanol and ethanol solvates of 4-glutarato-<i>N</i>,<i>N</i>-diiso-propyl-tryptamine.PMC9535823Bauer BEManke DRChadeayne ARNaeem MGolen JAfalseThe methanol and ethanol solvates of 4-glutarato-<i>N</i>,<i>N</i>-diiso-propyl-tryptamine.The solid-state structures of two solvated forms of 4-glutarato-<i>N</i>,<i>N</i>-diiso-propyl-tryptamine were determined by single-crystal X-ray diffraction, namely, 5-[(3-{2-[bis(propan-2-yl)azaniumyl]ethyl}-1<i>H</i>-indol-4-yl)oxy]-5-oxopentanoate meth-anol monosolvate, C₂₁H₃₀N₂O₄·CH₃OH, and the analogous ethanol monosolvate, C₂₁H₃₀N₂O₄·C₂H₆O. In both compounds, the 4-glutarato-<i>N</i>,<i>N</i>-di-iso--pro-pyl-tryptamine exists as a zwitterion with a protonated tertiary ammonium and a deprotonated glutarato carboxyl-ate. The tryptamine zwitterions and alcohol solvates in both structures combine to produce near identical hydrogen-bonding networks, with N-H⋯O and O-H⋯2022-01-01T00:00:00Z2022 Oct2025-04-18T22:37:07.384Z2025-04-07T10:23:00.918ZS-EPMC95358233625012210.1107/S2056989022009094