{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["42(10)"],"submitter":["Kern KC"],"pubmed_abstract":["Post-stroke cognitive impairment is related to the effects of the acute stroke and pre-stroke brain health. We tested whether diffusion tensor imaging (DTI) can detect acute, global effects of stroke and predict post-stroke cognitive performance. Patients with stroke or TIA enrolled in a prospective cohort study were included if they had 1) at least one DTI acquisition at acute presentation, 24 hours, 5 days, or 30 days, and 2) follow-up testing with the telephone Montreal Cognitive Assessment (T-MoCA) at 30 and/or 90 days. A whole brain, white-matter skeleton excluding the infarct was used to derive mean global DTI measures for mean diffusivity (MD), fractional anisotropy (FA), free water (FW), FW-corrected MD (MD<sub>tissue</sub>), and FW-corrected FA (FA<sub>tissue</sub>). In 74 patient"],"journal":["Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism"],"pagination":["1854-1866"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9536124"],"repository":["biostudies-literature"],"pubmed_title":["Global changes in diffusion tensor imaging during acute ischemic stroke and post-stroke cognitive performance."],"pmcid":["PMC9536124"],"pubmed_authors":["Kern KC","Leigh R","Wright CB"],"additional_accession":[]},"is_claimable":false,"name":"Global changes in diffusion tensor imaging during acute ischemic stroke and post-stroke cognitive performance.","description":"Post-stroke cognitive impairment is related to the effects of the acute stroke and pre-stroke brain health. We tested whether diffusion tensor imaging (DTI) can detect acute, global effects of stroke and predict post-stroke cognitive performance. Patients with stroke or TIA enrolled in a prospective cohort study were included if they had 1) at least one DTI acquisition at acute presentation, 24 hours, 5 days, or 30 days, and 2) follow-up testing with the telephone Montreal Cognitive Assessment (T-MoCA) at 30 and/or 90 days. A whole brain, white-matter skeleton excluding the infarct was used to derive mean global DTI measures for mean diffusivity (MD), fractional anisotropy (FA), free water (FW), FW-corrected MD (MD<sub>tissue</sub>), and FW-corrected FA (FA<sub>tissue</sub>). In 74 patient","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2026-07-14T16:58:53.892Z","creation":"2025-04-04T03:42:46.61Z"},"accession":"S-EPMC9536124","cross_references":{"pubmed":["35579236"],"doi":["10.1177/0271678x221101644","10.1177/0271678X221101644"]}}