biostudies-literaturePayne SNIA NIH HHS1643-1654https://www.ebi.ac.uk/biostudies/studies/S-EPMC9536845biostudies-literatureUnknown86(4)<h4>Background</h4>Many patients with dementia with Lewy bodies (DLB) miss out on the best standards of care and psychosocial support due to diagnostic delays or inaccuracies following symptom onset.<h4>Objective</h4>This study seeks to identify baseline characteristics in individuals with mild cognitive impairment (MCI) that correlate with eventual conversion to DLB or Alzheimer's disease (AD).<h4>Methods</h4>Baseline neuropsychological and neuropsychiatric data were analyzed in National Alzheimer's Coordinating Center participants who completed the Uniform Data Set between 2006 and 2020 and subsequently converted from MCI to DLB or AD (n = 1632).<h4>Results</h4>Only 6% of participants with MCI converted to DLB. Among those who converted to DLB, multidomain amnestic MCI (aMCI) was the mosJournal of Alzheimer's disease : JADCorrelates of Conversion from Mild Cognitive Impairment to Dementia with Lewy Bodies: Data from the National Alzheimer's Coordinating Center.PMC9536845P30 AG013846P30 AG028383P30 AG008017P30 AG053760P30 AG010133P50 AG005146P50 AG033514P50 AG005681P50 AG005142P50 AG047366P50 AG047266P30 AG019610P50 AG023501P30 AG008051P30 AG010129R21 AG064271P30 AG013854P50 AG005138P50 AG008702P30 AG010124P30 AG012300P50 AG005134U01 AG016976P50 AG005136P50 AG025688P30 AG035982P30 AG010161P50 AG005131P50 AG005133P30 AG049638P50 AG016574P50 AG016573Shofer JBLi GShutes-David AJankowski APayne SDean PTsuang DfalseCorrelates of Conversion from Mild Cognitive Impairment to Dementia with Lewy Bodies: Data from the National Alzheimer's Coordinating Center.<h4>Background</h4>Many patients with dementia with Lewy bodies (DLB) miss out on the best standards of care and psychosocial support due to diagnostic delays or inaccuracies following symptom onset.<h4>Objective</h4>This study seeks to identify baseline characteristics in individuals with mild cognitive impairment (MCI) that correlate with eventual conversion to DLB or Alzheimer's disease (AD).<h4>Methods</h4>Baseline neuropsychological and neuropsychiatric data were analyzed in National Alzheimer's Coordinating Center participants who completed the Uniform Data Set between 2006 and 2020 and subsequently converted from MCI to DLB or AD (n = 1632).<h4>Results</h4>Only 6% of participants with MCI converted to DLB. Among those who converted to DLB, multidomain amnestic MCI (aMCI) was the mos2022-01-01T00:00:00Z20222025-04-19T17:36:06.423Z2025-02-19T00:27:06.906ZS-EPMC95368453521337410.3233/jad-21542810.3233/JAD-215428