biostudies-literatureUnknown4(3)Ganatra S<h4>Background</h4>Racial and social disparities exist in outcomes related to cancer and cardiovascular disease (CVD).<h4>Objectives</h4>The aim of this cross-sectional study was to study the impact of social vulnerability on mortality attributed to comorbid cancer and CVD.<h4>Methods</h4>The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database (2015-2019) was used to obtain county-level mortality data attributed to cancer, CVD, and comorbid cancer and CVD. County-level social vulnerability index (SVI) data (2014-2018) were obtained from the CDC's Agency for Toxic Substances and Disease Registry. SVI percentiles were generated for each county and aggregated to form SVI quartiles. Age-adjusted mortality rates (AAMRs) were estimated and compJACC. CardioOncology326-337https://www.ebi.ac.uk/biostudies/studies/S-EPMC9537091biostudies-literatureImpact of Social Vulnerability on Comorbid Cancer and Cardiovascular Disease Mortality in the United States.PMC9537091Virani SSKazi DSadler DDani SSBaron SJLeja MDeswal ALiu JEStevens JGanatra SHayek SSGupta DKy BHermann JFradley MGuha ABarac ABrown SAKalra ANasir KWadhera RBaldassarre LAThavendiranathan PKhan SUYang EAsnani ANohria AKumar APorter CNeilan TGfalseImpact of Social Vulnerability on Comorbid Cancer and Cardiovascular Disease Mortality in the United States.<h4>Background</h4>Racial and social disparities exist in outcomes related to cancer and cardiovascular disease (CVD).<h4>Objectives</h4>The aim of this cross-sectional study was to study the impact of social vulnerability on mortality attributed to comorbid cancer and CVD.<h4>Methods</h4>The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database (2015-2019) was used to obtain county-level mortality data attributed to cancer, CVD, and comorbid cancer and CVD. County-level social vulnerability index (SVI) data (2014-2018) were obtained from the CDC's Agency for Toxic Substances and Disease Registry. SVI percentiles were generated for each county and aggregated to form SVI quartiles. Age-adjusted mortality rates (AAMRs) were estimated and comp2022-01-01T00:00:00Z2022 Sep2025-04-25T17:38:08.873Z2025-04-06T05:27:00.026ZS-EPMC95370913621335710.1016/j.jaccao.2022.06.005