{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Nham E"],"pubmed_abstract":["<h4>Introduction</h4>Despite vaccine development, the COVID-19 pandemic is ongoing due to immunity-escaping variants of concern (VOCs). Estimations of vaccine-induced protective immunity against VOCs are essential for setting proper COVID-19 vaccination policy.<h4>Methods</h4>We performed plaque-reduction neutralizing tests (PRNTs) using sera from healthcare workers (HCWs) collected from baseline to six months after COVID-19 vaccination and from convalescent COVID-19 patients. The 20.2% of the mean PRNT titer of convalescent sera was used as 50% protective value, and the percentage of HCWs with protective immunity for each week (percent-week) was compared among vaccination groups. A correlation equation was deduced between a PRNT 50% neutralizing dose (ND<sub>50</sub>) against wild type (W"],"journal":["Frontiers in immunology"],"pagination":["968105"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9538478"],"repository":["biostudies-literature"],"pubmed_title":["Kinetics of vaccine-induced neutralizing antibody titers and estimated protective immunity against wild-type SARS-CoV-2 and the Delta variant: A prospective nationwide cohort study comparing three COVID-19 vaccination protocols in South Korea."],"pmcid":["PMC9538478"],"pubmed_authors":["Park YS","Kim SW","Kim B","Kim SS","Ko JH","Kang ES","Kim ES","Kim SH","Song YG","Bae S","Peck KR","Jang HC","Kim KC","Ahn JY","Song KH","Kim HJ","Nham E","Lim HY","Kwon KT","Baek YJ","Kim YC","Jeong HW","Choi JY","Choi WS","Lee KH"],"additional_accession":[]},"is_claimable":false,"name":"Kinetics of vaccine-induced neutralizing antibody titers and estimated protective immunity against wild-type SARS-CoV-2 and the Delta variant: A prospective nationwide cohort study comparing three COVID-19 vaccination protocols in South Korea.","description":"<h4>Introduction</h4>Despite vaccine development, the COVID-19 pandemic is ongoing due to immunity-escaping variants of concern (VOCs). Estimations of vaccine-induced protective immunity against VOCs are essential for setting proper COVID-19 vaccination policy.<h4>Methods</h4>We performed plaque-reduction neutralizing tests (PRNTs) using sera from healthcare workers (HCWs) collected from baseline to six months after COVID-19 vaccination and from convalescent COVID-19 patients. The 20.2% of the mean PRNT titer of convalescent sera was used as 50% protective value, and the percentage of HCWs with protective immunity for each week (percent-week) was compared among vaccination groups. A correlation equation was deduced between a PRNT 50% neutralizing dose (ND<sub>50</sub>) against wild type (W","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T14:34:37.978Z","creation":"2025-04-04T14:34:37.978Z"},"accession":"S-EPMC9538478","cross_references":{"pubmed":["36211416"],"doi":["10.3389/fimmu.2022.968105"]}}