biostudies-literatureTermannsen ADSteno Diabetes Center Copenhagen (SDCC)e13462https://www.ebi.ac.uk/biostudies/studies/S-EPMC9540559biostudies-literatureUnknown23(9)In parallel with an increased focus on climate changes and carbon footprint, the interest in plant-based diets and its potential health effects have increased over the past decade. The objective of this systematic review and meta-analysis was to examine the effect of vegan diets (≥12 weeks) on cardiometabolic risk factors in people with overweight or type 2 diabetes. We identified 11 trials (796 participants). In comparison with control diets, vegan diets reduced body weight (-4.1 kg, 95% confidence interval (CI) -5.9 to -2.4, p < 0.001), body mass index (BMI) (-1.38 kg/m² , 95% CI -1.96 to -0.80, p < 0.001), glycated hemoglobin (HbA_1c ) (-0.18% points, 95% CI -0.29 to -0.07, p = 0.002), total cholesterol (-0.30 mmol/L, 95% CI -0.52 to -0.08, p = 0.007), and low-densiObesity reviews : an official journal of the International Association for the Study of ObesityEffects of vegan diets on cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials.PMC9540559SDCC 3.GTermannsen ADNorgaard ODiaz LJTorekov SSFaerch KThomsen JMClemmensen KKBQuist JSfalseEffects of vegan diets on cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials.In parallel with an increased focus on climate changes and carbon footprint, the interest in plant-based diets and its potential health effects have increased over the past decade. The objective of this systematic review and meta-analysis was to examine the effect of vegan diets (≥12 weeks) on cardiometabolic risk factors in people with overweight or type 2 diabetes. We identified 11 trials (796 participants). In comparison with control diets, vegan diets reduced body weight (-4.1 kg, 95% confidence interval (CI) -5.9 to -2.4, p < 0.001), body mass index (BMI) (-1.38 kg/m² , 95% CI -1.96 to -0.80, p < 0.001), glycated hemoglobin (HbA_1c ) (-0.18% points, 95% CI -0.29 to -0.07, p = 0.002), total cholesterol (-0.30 mmol/L, 95% CI -0.52 to -0.08, p = 0.007), and low-densi2022-01-01T00:00:00Z2022 Sep2025-04-22T12:10:48.61Z2025-04-06T00:14:50.312ZS-EPMC95405593567294010.1111/obr.13462