{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20(8)"],"submitter":["Roberts JC"],"funding":["Novo Nordisk"],"pubmed_abstract":["<h4>Background</h4>Extremely premature neonates have increased risk for bleeding, perhaps the most devastating version of which being intraventricular hemorrhage (IVH). Limited data are available for coagulation parameters in this vulnerable population.<h4>Objectives</h4>We conducted a prospective cohort study characterizing coagulation laboratory parameters in extremely premature neonates 23-30 weeks gestational age (GA) and determined coagulation parameters and clinical risk factors associated with IVH.<h4>Patients/methods</h4>One hundred twenty neonates 23-30 weeks GA were enrolled, and umbilical cord blood samples were obtained and processed at the time of birth. Coagulation parameters including prothrombin time (PT), international normalized ratio (INR), activated partial thromboplast"],"journal":["Journal of thrombosis and haemostasis : JTH"],"pagination":["1797-1807"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9543331"],"repository":["biostudies-literature"],"pubmed_title":["Characterization of laboratory coagulation parameters and risk factors for intraventricular hemorrhage in extremely premature neonates."],"pmcid":["PMC9543331"],"pubmed_authors":["Roberts JC","Javed MJ","Lundy MK","Burns RM","Tarantino MD","Wang H"],"additional_accession":[]},"is_claimable":false,"name":"Characterization of laboratory coagulation parameters and risk factors for intraventricular hemorrhage in extremely premature neonates.","description":"<h4>Background</h4>Extremely premature neonates have increased risk for bleeding, perhaps the most devastating version of which being intraventricular hemorrhage (IVH). Limited data are available for coagulation parameters in this vulnerable population.<h4>Objectives</h4>We conducted a prospective cohort study characterizing coagulation laboratory parameters in extremely premature neonates 23-30 weeks gestational age (GA) and determined coagulation parameters and clinical risk factors associated with IVH.<h4>Patients/methods</h4>One hundred twenty neonates 23-30 weeks GA were enrolled, and umbilical cord blood samples were obtained and processed at the time of birth. Coagulation parameters including prothrombin time (PT), international normalized ratio (INR), activated partial thromboplast","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-22T02:02:01.369Z","creation":"2025-04-05T20:11:42.017Z"},"accession":"S-EPMC9543331","cross_references":{"pubmed":["35524764"],"doi":["10.1111/jth.15755"]}}