{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gundogdu B"],"funding":["Foundation for the National Institutes of Health","Comprehensive Cancer Center, University of Chicago Medical Center","NCI NIH HHS","NIH HHS"],"pagination":["2298-2310"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9545544"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["88(5)"],"pubmed_abstract":["Purpose
To evaluate and quantify inter-directional and inter-acquisition variation in diffusion-weighted imaging (DWI) and emphasize signals that report restricted diffusion to enhance cancer conspicuity, while reducing the effects of local microscopic motion and magnetic field fluctuations.Methods
Ten patients with biopsy-proven prostate cancer were studied under an Institutional Review Board-approved protocol. Individual acquisitions of DWI signal intensities were reconstructed to calculate inter-acquisition distributions and their statistics, which were compared for healthy versus cancer tissue. A method was proposed to detect and filter the acquisitions affected by motion-induced signal loss. First, signals that reflect restricted diffusion were separated from the acqui"],"journal":["Magnetic resonance in medicine"],"pubmed_title":["Directional and inter-acquisition variability in diffusion-weighted imaging and editing for restricted diffusion."],"pmcid":["PMC9545544"],"funding_grant_id":["1R41CA244056‐01A1","R01 CA227036","R01 CA17280","R01 CA122706","1S10OD018448‐01","R41 CA244056","P30 CA014599‐37","P30 CA014599","S10 OD018448"],"pubmed_authors":["Fan X","Oto A","Karczmar GS","Guo X","Yousuf A","Antic T","Chatterjee A","Pittman JM","Giurcanu M","Lee G","Devaraj A","Szasz T","Medved M","Gundogdu B","Engelmann R"],"additional_accession":[]},"is_claimable":false,"name":"Directional and inter-acquisition variability in diffusion-weighted imaging and editing for restricted diffusion.","description":"Purpose
To evaluate and quantify inter-directional and inter-acquisition variation in diffusion-weighted imaging (DWI) and emphasize signals that report restricted diffusion to enhance cancer conspicuity, while reducing the effects of local microscopic motion and magnetic field fluctuations.Methods
Ten patients with biopsy-proven prostate cancer were studied under an Institutional Review Board-approved protocol. Individual acquisitions of DWI signal intensities were reconstructed to calculate inter-acquisition distributions and their statistics, which were compared for healthy versus cancer tissue. A method was proposed to detect and filter the acquisitions affected by motion-induced signal loss. First, signals that reflect restricted diffusion were separated from the acqui","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-19T04:46:08.633Z","creation":"2025-04-19T04:46:08.633Z"},"accession":"S-EPMC9545544","cross_references":{"pubmed":["35861268"],"doi":["10.1002/mrm.29385"]}}