{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["101(2)"],"submitter":["Carsetti R"],"pubmed_abstract":["The B cell compartment provides innate and adaptive immune defenses against pathogens. Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals. A specific gating strategy is also described to clearly and univocally identify B cell subsets based on the their phenotypic traits by flow cytometric analysis."],"journal":["Cytometry. Part A : the journal of the International Society for Analytical Cytology"],"pagination":["131-139"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9546334"],"repository":["biostudies-literature"],"pubmed_title":["Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions."],"pmcid":["PMC9546334"],"pubmed_authors":["Terreri S","Corrente F","Fernandez Salinas A","Piano Mortari E","Conti MG","Capponi C","Albano C","Carsetti R"],"additional_accession":[]},"is_claimable":false,"name":"Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions.","description":"The B cell compartment provides innate and adaptive immune defenses against pathogens. Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals. A specific gating strategy is also described to clearly and univocally identify B cell subsets based on the their phenotypic traits by flow cytometric analysis.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2025-04-22T12:09:20.327Z","creation":"2025-04-06T00:12:33.467Z"},"accession":"S-EPMC9546334","cross_references":{"pubmed":["34664397"],"doi":["10.1002/cyto.a.24507"]}}