biostudies-literatureUnknown9Garcia R<h4>Background</h4>The pathophysiology of persistent atrial fibrillation (AF) remains unclear. While several studies have demonstrated an association between myocardial infarction and atrial fibrillation, the role of stable coronary artery disease (CAD) is still unknown. As a result, we aimed to assess the association between CAD obstruction and AF recurrence after persistent AF ablation in patients with no history of CAD.<h4>Materials and methods</h4>This observational retrospective study included consecutive patients who underwent routine preprocedural cardiac computed tomography (CCT) before persistent AF ablation between September 2015 and June 2018 in 5 European University Hospitals. Exclusion criteria were CAD or coronary revascularization previously known or during follow-up. ObstruFrontiers in cardiovascular medicine873135https://www.ebi.ac.uk/biostudies/studies/S-EPMC9548703biostudies-literatureAsymptomatic left circumflex artery stenosis is associated with higher arrhythmia recurrence after persistent atrial fibrillation ablation.PMC9548703Plank FDegand BSakhy SSimon JLaurent GMarijon EGarcia RPhilibert SChristiaens LGuenancia CStuhlinger MHerczeg SGras MSzegedi NPoupin PClouard MCrijns HJGMfalseAsymptomatic left circumflex artery stenosis is associated with higher arrhythmia recurrence after persistent atrial fibrillation ablation.<h4>Background</h4>The pathophysiology of persistent atrial fibrillation (AF) remains unclear. While several studies have demonstrated an association between myocardial infarction and atrial fibrillation, the role of stable coronary artery disease (CAD) is still unknown. As a result, we aimed to assess the association between CAD obstruction and AF recurrence after persistent AF ablation in patients with no history of CAD.<h4>Materials and methods</h4>This observational retrospective study included consecutive patients who underwent routine preprocedural cardiac computed tomography (CCT) before persistent AF ablation between September 2015 and June 2018 in 5 European University Hospitals. Exclusion criteria were CAD or coronary revascularization previously known or during follow-up. Obstru2022-01-01T00:00:00Z20222025-04-04T21:41:39.553Z2025-04-04T21:41:39.553ZS-EPMC95487033622596010.3389/fcvm.2022.873135