{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ince YC"],"funding":["Université de Lausanne","Velux Stiftung","Swiss National Science Foundation","Agence Nationale de la Recherche","Fonds De La Recherche Scientifique - FNRS"],"pagination":["5659"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9550796"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(1)"],"pubmed_abstract":["Plant growth ultimately depends on fixed carbon, thus the available light for photosynthesis. Due to canopy light absorption properties, vegetative shade combines low blue (LB) light and a low red to far-red ratio (LRFR). In shade-avoiding plants, these two conditions independently trigger growth adaptations to enhance light access. However, how these conditions, differing in light quality and quantity, similarly promote hypocotyl growth remains unknown. Using RNA sequencing we show that these two features of shade trigger different transcriptional reprogramming. LB induces starvation responses, suggesting a switch to a catabolic state. Accordingly, LB promotes autophagy. In contrast, LRFR induced anabolism including expression of sterol biosynthesis genes in hypocotyls in a manner depende"],"journal":["Nature communications"],"pubmed_title":["A combination of plasma membrane sterol biosynthesis and autophagy is required for shade-induced hypocotyl elongation."],"pmcid":["PMC9550796"],"funding_grant_id":["ANR–11–INBS–0010","1455","310030_200318","2022/V 3/5/053-40010130-JG/JN-2724","179558","310030B_179558"],"pubmed_authors":["Krahmer J","Trevisan M","Ivanisevic J","Galvao VC","Mongrand S","Gallart-Ayala H","Pradervand S","Genva M","Van Delft P","Fouillen L","Wigger L","Fankhauser C","Ince YC","Fiorucci AS"],"additional_accession":[]},"is_claimable":false,"name":"A combination of plasma membrane sterol biosynthesis and autophagy is required for shade-induced hypocotyl elongation.","description":"Plant growth ultimately depends on fixed carbon, thus the available light for photosynthesis. Due to canopy light absorption properties, vegetative shade combines low blue (LB) light and a low red to far-red ratio (LRFR). In shade-avoiding plants, these two conditions independently trigger growth adaptations to enhance light access. However, how these conditions, differing in light quality and quantity, similarly promote hypocotyl growth remains unknown. Using RNA sequencing we show that these two features of shade trigger different transcriptional reprogramming. LB induces starvation responses, suggesting a switch to a catabolic state. Accordingly, LB promotes autophagy. In contrast, LRFR induced anabolism including expression of sterol biosynthesis genes in hypocotyls in a manner depende","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-04T09:30:15.35Z","creation":"2025-04-04T09:30:15.35Z"},"accession":"S-EPMC9550796","cross_references":{"pubmed":["36216814"],"doi":["10.1038/s41467-022-33384-9"]}}