biostudies-literatureUnknown16Modeling how patterns of light and dark affect circadian phase is important clinically and organizationally (e.g., the military) because circadian disruption can compromise health and performance. Limit-cycle oscillator models in various forms have been used to characterize phase changes to a limited set of light interventions. We approached the analysis of the van der Pol oscillator-based model proposed by Kronauer and colleagues in 1999 and 2000 (Kronauer99) using a well-established framework from experimental psychology whereby the stimulus (S) acts on the organism (O) to produce a response (R). Within that framework, using four independent data sets utilizing calibrated personal light measurements, we conducted a serial analysis of the factors in the Kronauer99 model that could affect Frontiers in neurosciencehttps://www.ebi.ac.uk/biostudies/studies/S-EPMC9552883biostudies-literatureThe circadian stimulus-oscillator model: Improvements to Kronauer’s model of the human circadian pacemakerPMC9552883falseThe circadian stimulus-oscillator model: Improvements to Kronauer’s model of the human circadian pacemakerModeling how patterns of light and dark affect circadian phase is important clinically and organizationally (e.g., the military) because circadian disruption can compromise health and performance. Limit-cycle oscillator models in various forms have been used to characterize phase changes to a limited set of light interventions. We approached the analysis of the van der Pol oscillator-based model proposed by Kronauer and colleagues in 1999 and 2000 (Kronauer99) using a well-established framework from experimental psychology whereby the stimulus (S) acts on the organism (O) to produce a response (R). Within that framework, using four independent data sets utilizing calibrated personal light measurements, we conducted a serial analysis of the factors in the Kronauer99 model that could affect 2022-01-01T00:00:00Z2022 Jan2025-04-05T11:37:59.938Z2025-02-19T01:02:28.783ZS-EPMC9552883