{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Bhuiyan TR"],"pubmed_abstract":["Coronavirus disease 2019 (COVID-19) is a protean disease causing different degrees of clinical severity including fatality. In addition to humoral immunity, antigen-specific T cells may play a critical role in defining the protective immune response against SARS-CoV-2, the virus that causes this disease. As a part of a longitudinal cohort study in Bangladesh to investigate B and T cell-specific immune responses, we sought to evaluate the activation-induced marker (AIM) and the status of different immune cell subsets during a COVID-19 infection. We analyzed a total of 115 participants, which included participants with asymptomatic, mild, moderate, and severe clinical symptoms. We observed decreased mucosal-associated invariant T (MAIT) cell frequency on the initial days of the COVID-19 infe"],"journal":["Frontiers in immunology"],"pagination":["929849"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9554593"],"repository":["biostudies-literature"],"pubmed_title":["Correlation of antigen-specific immune response with disease severity among COVID-19 patients in Bangladesh."],"pmcid":["PMC9554593"],"pubmed_authors":["Islam S","Sumon MA","Sette A","Qadri F","Bhuiyan TR","Akter A","Ahmed T","Rashed A","Chowdhury F","Karmakar PC","Hakim A","Clemens JD","Hasnat MA","Ghosh S","Weiskopf D","Banu S","Al Banna H","Shirin T","Tauheed I","Kaisar MH"],"additional_accession":[]},"is_claimable":false,"name":"Correlation of antigen-specific immune response with disease severity among COVID-19 patients in Bangladesh.","description":"Coronavirus disease 2019 (COVID-19) is a protean disease causing different degrees of clinical severity including fatality. In addition to humoral immunity, antigen-specific T cells may play a critical role in defining the protective immune response against SARS-CoV-2, the virus that causes this disease. As a part of a longitudinal cohort study in Bangladesh to investigate B and T cell-specific immune responses, we sought to evaluate the activation-induced marker (AIM) and the status of different immune cell subsets during a COVID-19 infection. We analyzed a total of 115 participants, which included participants with asymptomatic, mild, moderate, and severe clinical symptoms. We observed decreased mucosal-associated invariant T (MAIT) cell frequency on the initial days of the COVID-19 infe","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-18T22:52:36.027Z","creation":"2025-04-07T10:38:22.065Z"},"accession":"S-EPMC9554593","cross_references":{"pubmed":["36248882"],"doi":["10.3389/fimmu.2022.929849"]}}