biostudies-literatureUnknown12Li C<h4>Background</h4>Many studies have shown that metabolism-related lncRNAs may play an important role in the pathogenesis of colon cancer. In this study, a prognostic model for colon cancer patients was constructed based on metabolism-related lncRNAs.<h4>Methods</h4>Both transcriptome data and clinical data of colon cancer patients were downloaded from the TCGA database, and metabolism-related genes were downloaded from the GSEA database. Through differential expression analysis and Pearson correlation analysis, long non-coding RNAs (lncRNAs) related to colon cancer metabolism were obtained. CRC patients were divided into training set and verification set at the ratio of 2:1. Based on the training set, univariate Cox regression analysis was utilized to determine the prognostic differentialFrontiers in oncology944476https://www.ebi.ac.uk/biostudies/studies/S-EPMC9558288biostudies-literatureConstruction of a prognostic model of colon cancer patients based on metabolism-related lncRNAs.PMC9558288Li CZhang XLiu QWang WSong YfalseConstruction of a prognostic model of colon cancer patients based on metabolism-related lncRNAs.<h4>Background</h4>Many studies have shown that metabolism-related lncRNAs may play an important role in the pathogenesis of colon cancer. In this study, a prognostic model for colon cancer patients was constructed based on metabolism-related lncRNAs.<h4>Methods</h4>Both transcriptome data and clinical data of colon cancer patients were downloaded from the TCGA database, and metabolism-related genes were downloaded from the GSEA database. Through differential expression analysis and Pearson correlation analysis, long non-coding RNAs (lncRNAs) related to colon cancer metabolism were obtained. CRC patients were divided into training set and verification set at the ratio of 2:1. Based on the training set, univariate Cox regression analysis was utilized to determine the prognostic differential2022-01-01T00:00:00Z20222026-06-22T03:10:08.6Z2025-04-07T10:22:09.596ZS-EPMC95582883624898410.3389/fonc.2022.944476