{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(40)"],"submitter":["Wang R"],"pubmed_abstract":["Nanotechnology-applied materials and related therapeutics have gained attention for treating inflammatory skin diseases. The beach rose (<i>Rosa rugosa</i>), belonging to the family Rosaceae, is a perennial, deciduous woody shrub endemic to northeastern Asia. In this study, <i>R. rugosa</i>-based gold nanoparticles (RR-AuNPs) were biologically synthesized under optimal conditions to explore their potential as anti-inflammatory agents for treating skin inflammation. The synthesized RR-AuNPs were analyzed using field emission-transmission electron microscopy, energy-dispersive X-ray spectrometry, selected-area electron diffraction, and X-ray diffraction. The uniformly well-structured AuNPs showed near-spherical and polygonal shapes. Cell viability evaluation and optical observation results s"],"journal":["ACS omega"],"pagination":["35951-35960"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9558598"],"repository":["biostudies-literature"],"pubmed_title":["Biologically Synthesized <i>Rosa rugosa</i>-Based Gold Nanoparticles Suppress Skin Inflammatory Responses via MAPK and NF-κB Signaling Pathway in TNF-α/IFN-γ-Induced HaCaT Keratinocytes."],"pmcid":["PMC9558598"],"pubmed_authors":["Kim WJ","Dhandapani S","Wang R","Kim H","Kim YJ","Moon SK"],"additional_accession":[]},"is_claimable":false,"name":"Biologically Synthesized <i>Rosa rugosa</i>-Based Gold Nanoparticles Suppress Skin Inflammatory Responses via MAPK and NF-κB Signaling Pathway in TNF-α/IFN-γ-Induced HaCaT Keratinocytes.","description":"Nanotechnology-applied materials and related therapeutics have gained attention for treating inflammatory skin diseases. The beach rose (<i>Rosa rugosa</i>), belonging to the family Rosaceae, is a perennial, deciduous woody shrub endemic to northeastern Asia. In this study, <i>R. rugosa</i>-based gold nanoparticles (RR-AuNPs) were biologically synthesized under optimal conditions to explore their potential as anti-inflammatory agents for treating skin inflammation. The synthesized RR-AuNPs were analyzed using field emission-transmission electron microscopy, energy-dispersive X-ray spectrometry, selected-area electron diffraction, and X-ray diffraction. The uniformly well-structured AuNPs showed near-spherical and polygonal shapes. Cell viability evaluation and optical observation results s","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-18T22:38:59.273Z","creation":"2025-04-07T10:27:46.123Z"},"accession":"S-EPMC9558598","cross_references":{"pubmed":["36249362"],"doi":["10.1021/acsomega.2c04832"]}}