{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sharma-Oates A"],"funding":["Medical Research Council","National Institute for Health Research (NIHR)","European League Against Rheumatism"],"pagination":["346"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9558944"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["The prevalence of some immune-mediated diseases (IMDs) shows distinct differences between populations of different ethnicities. The aim of this study was to determine if the age at diagnosis of common IMDs also differed between different ethnic groups in the UK, suggestive of distinct influences of ethnicity on disease pathogenesis. This was a population-based retrospective primary care study. Linear regression provided unadjusted and adjusted estimates of age at diagnosis for common IMDs within the following ethnic groups: White, South Asian, African-Caribbean and Mixed-race/Other. Potential disease risk confounders in the association between ethnicity and diagnosis age including sex, smoking, body mass index and social deprivation (Townsend quintiles) were adjusted for. The analysis was "],"journal":["BMC medicine"],"pubmed_title":["Early onset of immune-mediated diseases in minority ethnic groups in the UK."],"pmcid":["PMC9558944"],"funding_grant_id":["MC_PC_17228","HDR-9001","MR/P021220/1","HDR-9006","MC_QA137853","HDR-9004","HDR-9002","HDR-9003"],"pubmed_authors":["Nirantharakumar K","Jain A","Zemedikun DT","Kumar K","Bravo L","Williams JA","Sharma-Oates A","Lord JM","Reynolds JA","Raza K","Cardoso VR","Gkoutos G"],"additional_accession":[]},"is_claimable":false,"name":"Early onset of immune-mediated diseases in minority ethnic groups in the UK.","description":"The prevalence of some immune-mediated diseases (IMDs) shows distinct differences between populations of different ethnicities. The aim of this study was to determine if the age at diagnosis of common IMDs also differed between different ethnic groups in the UK, suggestive of distinct influences of ethnicity on disease pathogenesis. This was a population-based retrospective primary care study. Linear regression provided unadjusted and adjusted estimates of age at diagnosis for common IMDs within the following ethnic groups: White, South Asian, African-Caribbean and Mixed-race/Other. Potential disease risk confounders in the association between ethnicity and diagnosis age including sex, smoking, body mass index and social deprivation (Townsend quintiles) were adjusted for. The analysis was ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-19T20:34:13.013Z","creation":"2025-04-19T20:34:13.013Z"},"accession":"S-EPMC9558944","cross_references":{"pubmed":["36224602"],"doi":["10.1186/s12916-022-02544-5"]}}