{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang X"],"funding":["Program of the Chengdu Research Base of Giant Panda Breeding","National Natural Science Foundation of China","National Nature Science Foundation of China"],"pagination":["2587"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9559482"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(19)"],"pubmed_abstract":["Maternal deprivation (MD) in early life induces dysbiosis in the host gut microbiota, which is a key determinant of abnormal behavior in stress model individuals. Compared with the early parenting environment of the wild, captive giant pandas face frequent and premature maternal separation. Will this lead to imbalance in intestinal flora and stress in captive giant pandas? The purpose of this research is to evaluate the possible adverse effects of the traditional parenting mode on the gut microbiota of captive giant pandas. The results showed that the frequent and premature maternal separation at early stages of the young did not change α and β diversity indices of the gut microbes, but it increased the relative abundance of s_<i>Clostridium_tetani</i> and s_<i>Clostridium_sp_</i>MSJ_8 (si"],"journal":["Animals : an open access journal from MDPI"],"pubmed_title":["Possible Effects of Early Maternal Separation on the Gut Microbiota of Captive Adult Giant Pandas."],"pmcid":["PMC9559482"],"funding_grant_id":["2020CPB-B05","32100386"],"pubmed_authors":["Ayala J","Liu Y","Zhang X","Wang D","An J","Cai Z","Hou R","Zhang M","Wang X"],"additional_accession":[]},"is_claimable":false,"name":"Possible Effects of Early Maternal Separation on the Gut Microbiota of Captive Adult Giant Pandas.","description":"Maternal deprivation (MD) in early life induces dysbiosis in the host gut microbiota, which is a key determinant of abnormal behavior in stress model individuals. Compared with the early parenting environment of the wild, captive giant pandas face frequent and premature maternal separation. Will this lead to imbalance in intestinal flora and stress in captive giant pandas? The purpose of this research is to evaluate the possible adverse effects of the traditional parenting mode on the gut microbiota of captive giant pandas. The results showed that the frequent and premature maternal separation at early stages of the young did not change α and β diversity indices of the gut microbes, but it increased the relative abundance of s_<i>Clostridium_tetani</i> and s_<i>Clostridium_sp_</i>MSJ_8 (si","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-09-01T03:09:11.694Z","creation":"2025-09-01T03:05:50.02Z"},"accession":"S-EPMC9559482","cross_references":{"pubmed":["36230328"],"doi":["10.3390/ani12192587"]}}