biostudies-literatureUnknown2(1)Schofield D<h4>Purpose</h4>To evaluate the impact of inherited retinal diseases (IRDs) on quality of life (QoL) using multiattributable health utilities derived from primary patient data.<h4>Design</h4>Cross-sectional observational study.<h4>Participants</h4>Seventy adult patients (mean age, 42.7 years) with IRD recruited from state-wide services in Australia.<h4>Methods</h4>Health utility values were calculated from the Assessment of Quality of Life 8-Dimension (AQoL-8D). Linear regressions were used to analyze the relationship between the 25-item and 39-item National Eye Institute Visual Function Questionnaires (NEI-VFQ-25 and NEI-VFQ-39, respectively) and health utilities from the AQoL-8D.<h4>Main outcome measures</h4>The AQoL-8D utility values were compared between the IRD cohort and population nOphthalmology science100106https://www.ebi.ac.uk/biostudies/studies/S-EPMC9560564biostudies-literaturePatient-Reported Health-Related Quality of Life in Individuals with Inherited Retinal Diseases.PMC9560564Schofield DMa AGrigg JWest SJamieson RVShrestha RTan OKraindler JJelovic DfalsePatient-Reported Health-Related Quality of Life in Individuals with Inherited Retinal Diseases.<h4>Purpose</h4>To evaluate the impact of inherited retinal diseases (IRDs) on quality of life (QoL) using multiattributable health utilities derived from primary patient data.<h4>Design</h4>Cross-sectional observational study.<h4>Participants</h4>Seventy adult patients (mean age, 42.7 years) with IRD recruited from state-wide services in Australia.<h4>Methods</h4>Health utility values were calculated from the Assessment of Quality of Life 8-Dimension (AQoL-8D). Linear regressions were used to analyze the relationship between the 25-item and 39-item National Eye Institute Visual Function Questionnaires (NEI-VFQ-25 and NEI-VFQ-39, respectively) and health utilities from the AQoL-8D.<h4>Main outcome measures</h4>The AQoL-8D utility values were compared between the IRD cohort and population n2022-01-01T00:00:00Z2022 Mar2025-04-04T23:02:23.123Z2025-04-04T23:02:23.123ZS-EPMC95605643624618810.1016/j.xops.2021.100106