biostudies-literatureUnknown9Alvarez-Pitti JBlood pressure changes during exercise are part of the physiological response to physical activity. Exercise stress testing can detect an exaggerated blood pressure response in children and adolescent. It is applied for certain clinical conditions, but is also commonly used as part of the assessment of athletes. The interpretation of blood pressure values in response to exercise during childhood and adolescence requires appropriate reference data. We discuss the available reference values and their limitations with regard to device, exercise protocol and normalization. While the link between an exaggerated blood pressure response and cardiovascular events and mortality has been demonstrated for adults, the situation is less clear for children and adolescents. We discuss the existing evidenFrontiers in cardiovascular medicine1004508https://www.ebi.ac.uk/biostudies/studies/S-EPMC9561233biostudies-literatureBlood pressure response to exercise in children and adolescents.PMC9561233Wojcik MGrabitz CWuhl ERadovanovic DDrozdz DBrzezinski MAlvarez-Pitti JHerceg-Cavrak VMelk AfalseBlood pressure response to exercise in children and adolescents.Blood pressure changes during exercise are part of the physiological response to physical activity. Exercise stress testing can detect an exaggerated blood pressure response in children and adolescent. It is applied for certain clinical conditions, but is also commonly used as part of the assessment of athletes. The interpretation of blood pressure values in response to exercise during childhood and adolescence requires appropriate reference data. We discuss the available reference values and their limitations with regard to device, exercise protocol and normalization. While the link between an exaggerated blood pressure response and cardiovascular events and mortality has been demonstrated for adults, the situation is less clear for children and adolescents. We discuss the existing eviden2022-01-01T00:00:00Z20222025-04-04T23:02:04.147Z2025-04-04T23:02:04.147ZS-EPMC95612333624747810.3389/fcvm.2022.1004508