{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Seo M"],"funding":["Korean Society of Neurogastroenterology and Motility","Ministry of Science and ICT, South Korea","National Research Foundation of Korea"],"pagination":["608-617"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9577571"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["28(4)"],"pubmed_abstract":["<h4>Background/aims</h4>Biofeedback therapy is widely used to treat patients with chronic constipation, especially those with dyssynergic defecation. Yet, the utility of high-resolution manometry with novel parameters in the prediction of biofeedback response has not been reported. Thus, we constructed a model for predicting biofeedback therapy responders by applying the concept of integrated pressurized volume in patients undergoing high-resolution anorectal manometry.<h4>Methods</h4>Seventy-one female patients (age: 48-68 years) with dyssynergic defecation who underwent initial high-resolution anorectal manometry and subsequent biofeedback therapy were enrolled. The manometry profiles were used to calculate the 3-dimensional integrated pressurized volumes by multiplying the distance, tim"],"journal":["Journal of neurogastroenterology and motility"],"pubmed_title":["Predicting Responsiveness to Biofeedback Therapy Using High-resolution Anorectal Manometry With Integrated Pressurized Volume."],"pmcid":["PMC9577571"],"funding_grant_id":["NRF-2021R1G1A100831","KSNM-12-012","KSNM-20-02"],"pubmed_authors":["Noh W","Ye BD","Hwang SW","Myung SJ","Choi KM","Lee J","Seo M","Seo SY","Yang DH","Yoon IJ","Yoon J","Kim DY","Jung KW","Yang SK","Joo S","Lee HJ","Park SH","Byeon JS"],"additional_accession":[]},"is_claimable":false,"name":"Predicting Responsiveness to Biofeedback Therapy Using High-resolution Anorectal Manometry With Integrated Pressurized Volume.","description":"<h4>Background/aims</h4>Biofeedback therapy is widely used to treat patients with chronic constipation, especially those with dyssynergic defecation. Yet, the utility of high-resolution manometry with novel parameters in the prediction of biofeedback response has not been reported. Thus, we constructed a model for predicting biofeedback therapy responders by applying the concept of integrated pressurized volume in patients undergoing high-resolution anorectal manometry.<h4>Methods</h4>Seventy-one female patients (age: 48-68 years) with dyssynergic defecation who underwent initial high-resolution anorectal manometry and subsequent biofeedback therapy were enrolled. The manometry profiles were used to calculate the 3-dimensional integrated pressurized volumes by multiplying the distance, tim","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-05-18T11:39:25.673Z","creation":"2025-04-05T11:39:54.103Z"},"accession":"S-EPMC9577571","cross_references":{"pubmed":["36250368"],"doi":["10.5056/jnm21137"]}}