biostudies-literatureUnknown9Kim SE<h4>Background</h4>This study aimed to investigate the prognostic value of left atrial (LA) strain in patients with significant mitral regurgitation (MR) after surgical mitral valve (MV) repair.<h4>Methods</h4>A total of 169 patients (age 55 ± 15 years, 88 men) with moderate or severe MR on echocardiogram at least 6 months after surgical MV repair for primary MR were studied. Two-dimensional, Doppler, and speckle tracking echocardiography including MR quantitative measures, chamber size, and LA strain were comprehensively analyzed. The primary outcome was a composite of cardiovascular death, heart failure hospitalization, and MV reoperation.<h4>Results</h4>During a median of 44.4 months [interquartile range (IQR): 18.7-70.3 months] of follow-up, 44 patients (26%) experienced clinical eventFrontiers in cardiovascular medicine985122https://www.ebi.ac.uk/biostudies/studies/S-EPMC9577607biostudies-literatureLeft atrial strain and clinical outcome in patients with significant mitral regurgitation after surgical mitral valve repair.PMC9577607Cho IKim DYHong GRKim SESeo JHa JWShim CYfalseLeft atrial strain and clinical outcome in patients with significant mitral regurgitation after surgical mitral valve repair.<h4>Background</h4>This study aimed to investigate the prognostic value of left atrial (LA) strain in patients with significant mitral regurgitation (MR) after surgical mitral valve (MV) repair.<h4>Methods</h4>A total of 169 patients (age 55 ± 15 years, 88 men) with moderate or severe MR on echocardiogram at least 6 months after surgical MV repair for primary MR were studied. Two-dimensional, Doppler, and speckle tracking echocardiography including MR quantitative measures, chamber size, and LA strain were comprehensively analyzed. The primary outcome was a composite of cardiovascular death, heart failure hospitalization, and MV reoperation.<h4>Results</h4>During a median of 44.4 months [interquartile range (IQR): 18.7-70.3 months] of follow-up, 44 patients (26%) experienced clinical event2022-01-01T00:00:00Z20222025-04-19T21:18:06.753Z2025-04-19T21:18:06.753ZS-EPMC95776073626763910.3389/fcvm.2022.985122