{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(41)"],"submitter":["Mohamed AS"],"pubmed_abstract":["The synthesis with structural identifications including NMR and HRMS spectral data along with single-crystal X-ray diffraction analysis (for <b>20b</b>, <b>23b</b>, <b>25b</b>-<b>27b</b>) of a family of 14 new <i>syn</i>/<i>anti</i> bis-4-spiro-β-lactam-based unsaturated macrocycles (<b>19a</b>,<b>b-27a</b>,<b>b</b>), obtained by multistep synthesis including (i) diimine formation, (ii) Staudinger [2 + 2] ketene-imine cycloaddition, and (iii) ring-closing metathesis (RCM), is reported."],"journal":["ACS omega"],"pagination":["36795-36803"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9583306"],"repository":["biostudies-literature"],"pubmed_title":["Variable-Sized bis(4-spiro-fused-β-lactam)-Based Unsaturated Macrocycles: Synthesis and Characterization."],"pmcid":["PMC9583306"],"pubmed_authors":["Al-Awadhi FH","Mohamed AS","Al-Awadi NA"],"additional_accession":[]},"is_claimable":false,"name":"Variable-Sized bis(4-spiro-fused-β-lactam)-Based Unsaturated Macrocycles: Synthesis and Characterization.","description":"The synthesis with structural identifications including NMR and HRMS spectral data along with single-crystal X-ray diffraction analysis (for <b>20b</b>, <b>23b</b>, <b>25b</b>-<b>27b</b>) of a family of 14 new <i>syn</i>/<i>anti</i> bis-4-spiro-β-lactam-based unsaturated macrocycles (<b>19a</b>,<b>b-27a</b>,<b>b</b>), obtained by multistep synthesis including (i) diimine formation, (ii) Staudinger [2 + 2] ketene-imine cycloaddition, and (iii) ring-closing metathesis (RCM), is reported.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-26T00:54:21.177Z","creation":"2025-02-19T03:02:06.493Z"},"accession":"S-EPMC9583306","cross_references":{"pubmed":["36278047"],"doi":["10.1021/acsomega.2c05212"]}}