{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sanders ZB"],"funding":["Royal Society","Wellcome Trust"],"pagination":["3391-3404"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9586541"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["145(10)"],"pubmed_abstract":["Real-time functional MRI neurofeedback allows individuals to self-modulate their ongoing brain activity. This may be a useful tool in clinical disorders that are associated with altered brain activity patterns. Motor impairment after stroke has previously been associated with decreased laterality of motor cortex activity. Here we examined whether chronic stroke survivors were able to use real-time fMRI neurofeedback to increase laterality of motor cortex activity and assessed effects on motor performance and on brain structure and function. We carried out a randomized, double-blind, sham-controlled trial (ClinicalTrials.gov: NCT03775915) in which 24 chronic stroke survivors with mild to moderate upper limb impairment experienced three training days of either Real (n = 12) or Sham (n = 12) "],"journal":["Brain : a journal of neurology"],"pubmed_title":["Self-modulation of motor cortex activity after stroke: a randomized controlled trial."],"pmcid":["PMC9586541"],"funding_grant_id":["203139/Z/16/Z","102584/Z/13/Z","110027/Z/15/Z"],"pubmed_authors":["Fleming MK","Luhrs M","Smejka T","Johansen-Berg H","Sanders ZB","Goebel R","Sampaio-Baptista C","Marzolla MC","Zich C","Rieger SW"],"additional_accession":[]},"is_claimable":false,"name":"Self-modulation of motor cortex activity after stroke: a randomized controlled trial.","description":"Real-time functional MRI neurofeedback allows individuals to self-modulate their ongoing brain activity. This may be a useful tool in clinical disorders that are associated with altered brain activity patterns. Motor impairment after stroke has previously been associated with decreased laterality of motor cortex activity. Here we examined whether chronic stroke survivors were able to use real-time fMRI neurofeedback to increase laterality of motor cortex activity and assessed effects on motor performance and on brain structure and function. We carried out a randomized, double-blind, sham-controlled trial (ClinicalTrials.gov: NCT03775915) in which 24 chronic stroke survivors with mild to moderate upper limb impairment experienced three training days of either Real (n = 12) or Sham (n = 12) ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2026-05-28T05:44:53.038Z","creation":"2024-10-17T22:33:10.244Z"},"accession":"S-EPMC9586541","cross_references":{"pubmed":["35960166"],"doi":["10.1093/brain/awac239"]}}