{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Luo Y"],"funding":["West China Nursing Discipline Development Special Fund Project, Sichuan University"],"pagination":["895"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9587612"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["<h4>Background</h4>Infection is one of the most common causes of death in patients with hematological malignancies during chemotherapy. Due to its special location, local warmth and humidity, repeated pollution with stool and urine, and characteristically wrinkled anatomical structure within which bacteria can hide, the perianal becomes a site with a high incidence of infection. Such infection also has a high recurrence rate and high mortality, increasing the economic burden of patients, delaying the time of treatment and reducing the quality of life. In severe cases, sepsis occurs and endangers the patient's life. Previous studies have confirmed the effectiveness of povidone iodine (PI) in the prevention of perianal infection in patients with hematological malignancies during chemotherapy"],"journal":["Trials"],"pubmed_title":["Comparison of different concentrations of a povidone iodine-diluted sitz bath in the prevention of perianal infection in patients undergoing chemotherapy for hematological malignancy: study protocol for a randomized controlled trial."],"pmcid":["PMC9587612"],"funding_grant_id":["HXHL20034"],"pubmed_authors":["Zhou L","Li Y","Fang J","Yang M","Leng Y","Chen F","Luo Y","Wang Y","Chen C","Luo T"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of different concentrations of a povidone iodine-diluted sitz bath in the prevention of perianal infection in patients undergoing chemotherapy for hematological malignancy: study protocol for a randomized controlled trial.","description":"<h4>Background</h4>Infection is one of the most common causes of death in patients with hematological malignancies during chemotherapy. Due to its special location, local warmth and humidity, repeated pollution with stool and urine, and characteristically wrinkled anatomical structure within which bacteria can hide, the perianal becomes a site with a high incidence of infection. Such infection also has a high recurrence rate and high mortality, increasing the economic burden of patients, delaying the time of treatment and reducing the quality of life. In severe cases, sepsis occurs and endangers the patient's life. Previous studies have confirmed the effectiveness of povidone iodine (PI) in the prevention of perianal infection in patients with hematological malignancies during chemotherapy","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-26T00:50:45.394Z","creation":"2024-12-03T23:42:15.103Z"},"accession":"S-EPMC9587612","cross_references":{"pubmed":["36273160"],"doi":["10.1186/s13063-022-06721-y"]}}