{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chock VY"],"funding":["NHLBI NIH HHS"],"pagination":["1034-1041"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9588487"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["92(4)"],"pubmed_abstract":["<h4>Background</h4>Extremely low birth weight (ELBW) infants are at risk for end-organ hypoxia and ischemia. Regional tissue oxygenation of the brain and gut as monitored with near-infrared spectroscopy (NIRS) may change with postnatal age, but normal ranges are not well defined.<h4>Methods</h4>A prospective study of ELBW preterm infants utilized NIRS monitoring to assess changes in cerebral and mesenteric saturation (Csat and Msat) over the first week after birth. This secondary study of a multicenter trial comparing hemoglobin transfusion thresholds assessed cerebral and mesenteric fractional tissue oxygen extraction (cFTOE and mFTOE) and relationships with perinatal variables.<h4>Results</h4>In 124 infants, both Csat and Msat declined over the first week, with a corresponding increase i"],"journal":["Pediatric research"],"pubmed_title":["Early brain and abdominal oxygenation in extremely low birth weight infants."],"pmcid":["PMC9588487"],"funding_grant_id":["R01 HL122167"],"pubmed_authors":["Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network","Sokol GM","Higgins RD","Carlo WA","Kirpalani H","D'Angio CT","Seabrook RB","Chawla S","Yoder BA","Widness JA","Bell EF","Cotten CM","Van Meurs KP","Smith E","Walsh MC","Mancini T","Ball MB","Kennedy KA","Chalak LF","Ohls RK","Chock VY","Laptook AR","Tan S","Poindexter BB","Das A","Patel RM","Hintz SR"],"additional_accession":[]},"is_claimable":false,"name":"Early brain and abdominal oxygenation in extremely low birth weight infants.","description":"<h4>Background</h4>Extremely low birth weight (ELBW) infants are at risk for end-organ hypoxia and ischemia. Regional tissue oxygenation of the brain and gut as monitored with near-infrared spectroscopy (NIRS) may change with postnatal age, but normal ranges are not well defined.<h4>Methods</h4>A prospective study of ELBW preterm infants utilized NIRS monitoring to assess changes in cerebral and mesenteric saturation (Csat and Msat) over the first week after birth. This secondary study of a multicenter trial comparing hemoglobin transfusion thresholds assessed cerebral and mesenteric fractional tissue oxygen extraction (cFTOE and mFTOE) and relationships with perinatal variables.<h4>Results</h4>In 124 infants, both Csat and Msat declined over the first week, with a corresponding increase i","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-05T11:57:11.418Z","creation":"2025-04-05T11:57:11.418Z"},"accession":"S-EPMC9588487","cross_references":{"pubmed":["35513716"],"doi":["10.1038/s41390-022-02082-z"]}}