{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2022"],"submitter":["Sangeetha T"],"pubmed_abstract":["<h4>Background</h4>Anemia is one of the predominant hematological conditions, whereas chronic obstructive pulmonary disease (COPD) is a predominant respiratory disease. These two diseases were found to be interlinked, but the physiological pathways are still unclear.<h4>Aim</h4>The current study has been aimed at analysing the genetic interrelationship between anemia and COPD in accordance with different altitudes. <i>Methodology</i>. The genetic analysis was performed in the <i>SERPINA1</i> gene of anemia, COPD, and healthy individuals for the analysis of single nucleotide polymorphism at rs28949274 and rs17580 locations. <i>Result and Discussion</i>. The single nucleotide polymorphism at the locations rs28949274 and rs17580 was present in both anemic and COPD patients. The COPD patients "],"journal":["Journal of the renin-angiotensin-aldosterone system : JRAAS"],"pagination":["2238320"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9592209"],"repository":["biostudies-literature"],"pubmed_title":["Influence of <i>SERPINA1</i> Gene Polymorphisms on Anemia and Chronic Obstructive Pulmonary Disease."],"pmcid":["PMC9592209"],"pubmed_authors":["Nargis Begum T","Rengasamy KRR","Velayuthaprabhu S","Saradhadevi M","Sangeetha T","Vijaya Anand A","Senthilkumar N","Balamuralikrishnan B","Arun M","Sampathkumar P"],"additional_accession":[]},"is_claimable":false,"name":"Influence of <i>SERPINA1</i> Gene Polymorphisms on Anemia and Chronic Obstructive Pulmonary Disease.","description":"<h4>Background</h4>Anemia is one of the predominant hematological conditions, whereas chronic obstructive pulmonary disease (COPD) is a predominant respiratory disease. These two diseases were found to be interlinked, but the physiological pathways are still unclear.<h4>Aim</h4>The current study has been aimed at analysing the genetic interrelationship between anemia and COPD in accordance with different altitudes. <i>Methodology</i>. The genetic analysis was performed in the <i>SERPINA1</i> gene of anemia, COPD, and healthy individuals for the analysis of single nucleotide polymorphism at rs28949274 and rs17580 locations. <i>Result and Discussion</i>. The single nucleotide polymorphism at the locations rs28949274 and rs17580 was present in both anemic and COPD patients. The COPD patients ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-05T14:54:33.635Z","creation":"2025-04-05T14:54:33.635Z"},"accession":"S-EPMC9592209","cross_references":{"pubmed":["36320441"],"doi":["10.1155/2022/2238320"]}}