biostudies-literatureUnknown2022Sangeetha T<h4>Background</h4>Anemia is one of the predominant hematological conditions, whereas chronic obstructive pulmonary disease (COPD) is a predominant respiratory disease. These two diseases were found to be interlinked, but the physiological pathways are still unclear.<h4>Aim</h4>The current study has been aimed at analysing the genetic interrelationship between anemia and COPD in accordance with different altitudes. <i>Methodology</i>. The genetic analysis was performed in the <i>SERPINA1</i> gene of anemia, COPD, and healthy individuals for the analysis of single nucleotide polymorphism at rs28949274 and rs17580 locations. <i>Result and Discussion</i>. The single nucleotide polymorphism at the locations rs28949274 and rs17580 was present in both anemic and COPD patients. The COPD patients Journal of the renin-angiotensin-aldosterone system : JRAAS2238320https://www.ebi.ac.uk/biostudies/studies/S-EPMC9592209biostudies-literatureInfluence of <i>SERPINA1</i> Gene Polymorphisms on Anemia and Chronic Obstructive Pulmonary Disease.PMC9592209Nargis Begum TRengasamy KRRVelayuthaprabhu SSaradhadevi MSangeetha TVijaya Anand ASenthilkumar NBalamuralikrishnan BArun MSampathkumar PfalseInfluence of <i>SERPINA1</i> Gene Polymorphisms on Anemia and Chronic Obstructive Pulmonary Disease.<h4>Background</h4>Anemia is one of the predominant hematological conditions, whereas chronic obstructive pulmonary disease (COPD) is a predominant respiratory disease. These two diseases were found to be interlinked, but the physiological pathways are still unclear.<h4>Aim</h4>The current study has been aimed at analysing the genetic interrelationship between anemia and COPD in accordance with different altitudes. <i>Methodology</i>. The genetic analysis was performed in the <i>SERPINA1</i> gene of anemia, COPD, and healthy individuals for the analysis of single nucleotide polymorphism at rs28949274 and rs17580 locations. <i>Result and Discussion</i>. The single nucleotide polymorphism at the locations rs28949274 and rs17580 was present in both anemic and COPD patients. The COPD patients 2022-01-01T00:00:00Z20222025-04-05T14:54:33.635Z2025-04-05T14:54:33.635ZS-EPMC95922093632044110.1155/2022/2238320