{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(20)"],"submitter":["Grana-Baumgartner A"],"funding":["C. Alma Baker Trust","Massey University","L.A. Alexander Trust"],"pubmed_abstract":["During cold exposure, brown adipose tissue (BAT) holds the key mechanism in the generation of heat, thus inducing thermogenic adaptation in response to cooler environmental changes. This process can lead to a major lipidome remodelling in BAT, where the increase in abundance of many lipid classes plays a significant role in the thermogenic mechanisms for heat production. This study aimed to identify different types of lipids, through liquid chromatography-mass spectrometry (LC-MS), in BAT and plasma during a short-term cold challenge (2-days), or not, in new-born lambs. Fifteen new-born Romney lambs were selected randomly and divided into three groups: Group 1 (<i>n</i> = 3) with BAT and plasma obtained within 24 h after birth, as a control; Group 2 (<i>n</i> = 6) kept indoors for two days"],"journal":["Animals : an open access journal from MDPI"],"pagination":["2762"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9597848"],"repository":["biostudies-literature"],"pubmed_title":["Mass Spectrometry-Based Lipidomics of Brown Adipose Tissue and Plasma of New-Born Lambs Subjected to Short-Term Cold Exposure."],"pmcid":["PMC9597848"],"pubmed_authors":["Grana-Baumgartner A","Lopez-Villalobos N","Dukkipati VSR","Biggs PJ","Ross AB","Kenyon PR","Blair HT"],"additional_accession":[]},"is_claimable":false,"name":"Mass Spectrometry-Based Lipidomics of Brown Adipose Tissue and Plasma of New-Born Lambs Subjected to Short-Term Cold Exposure.","description":"During cold exposure, brown adipose tissue (BAT) holds the key mechanism in the generation of heat, thus inducing thermogenic adaptation in response to cooler environmental changes. This process can lead to a major lipidome remodelling in BAT, where the increase in abundance of many lipid classes plays a significant role in the thermogenic mechanisms for heat production. This study aimed to identify different types of lipids, through liquid chromatography-mass spectrometry (LC-MS), in BAT and plasma during a short-term cold challenge (2-days), or not, in new-born lambs. Fifteen new-born Romney lambs were selected randomly and divided into three groups: Group 1 (<i>n</i> = 3) with BAT and plasma obtained within 24 h after birth, as a control; Group 2 (<i>n</i> = 6) kept indoors for two days","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-03T21:30:43.874Z","creation":"2025-04-03T21:30:43.874Z"},"accession":"S-EPMC9597848","cross_references":{"pubmed":["36290148"],"doi":["10.3390/ani12202762"]}}