{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(20)"],"submitter":["Wang WH"],"pubmed_abstract":["<b>Background:</b> Historically, acute kidney injury (AKI) has been a common severe complication of acute myocardial infarction (MI). As percutaneous coronary interventions have become more widely used, AMI outcomes have significantly improved. However, post-AMI AKI epidemiology and its associated factors are not well-understood in the age of interventional cardiology. <b>Materials and methods:</b> This is a retrospective study examining changes in creatinine levels in all patients admitted for AMI in a single medical center between August 2009 and February 2019. KDIGO criteria were used to define the different stages of post-AMI AKI. <b>Results:</b> The study included 1299 eligible cases, among which 213 (16.4%) developed AKI during AMI index admission; and 128 (60.1%), 46 (21.6%), and 39 (18.3%) were classified as KDIGO stages 1, 2, and 3, respectively. Compared with non-AKI subjects, the AKI group had a higher prevalence of non-STEMI (48.4% vs. 29.1%, <i>p</i> &lt; 0.001), higher Killip class (3 or 4), and higher in-hospital mortality (15% vs. 2.5%, <i>p</i> &lt; 0.001). During the index MI hospitalization, 13.6% (29/213) of the post-MI AKI patients received hemodialysis. Baseline abnormal creatinine (≥1.5 mg/dL), dyslipidemia, and more advanced KDIGO stages (2 or 3) were associated with an increased risk of requiring in-hospital hemodialysis. Moreover, a more advanced KDIGO stage (≥2) was correlated with higher all-cause in-hospital mortality. <b>Conclusion:</b> AMI patients remain at risk of AKI, which negatively affects their survival in the modern age."],"journal":["Journal of clinical medicine"],"pagination":["6083"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9604918"],"repository":["biostudies-literature"],"pubmed_title":["Risk Factors and Outcome of Acute Kidney Injury following Acute Myocardial Infarction-A Case Series Study from 2009 to 2019."],"pmcid":["PMC9604918"],"pubmed_authors":["Hong YC","Wei KC","Lai PC","Chen HM","Wang WH","Chen D"],"additional_accession":[]},"is_claimable":false,"name":"Risk Factors and Outcome of Acute Kidney Injury following Acute Myocardial Infarction-A Case Series Study from 2009 to 2019.","description":"<b>Background:</b> Historically, acute kidney injury (AKI) has been a common severe complication of acute myocardial infarction (MI). As percutaneous coronary interventions have become more widely used, AMI outcomes have significantly improved. However, post-AMI AKI epidemiology and its associated factors are not well-understood in the age of interventional cardiology. <b>Materials and methods:</b> This is a retrospective study examining changes in creatinine levels in all patients admitted for AMI in a single medical center between August 2009 and February 2019. KDIGO criteria were used to define the different stages of post-AMI AKI. <b>Results:</b> The study included 1299 eligible cases, among which 213 (16.4%) developed AKI during AMI index admission; and 128 (60.1%), 46 (21.6%), and 39 (18.3%) were classified as KDIGO stages 1, 2, and 3, respectively. Compared with non-AKI subjects, the AKI group had a higher prevalence of non-STEMI (48.4% vs. 29.1%, <i>p</i> &lt; 0.001), higher Killip class (3 or 4), and higher in-hospital mortality (15% vs. 2.5%, <i>p</i> &lt; 0.001). During the index MI hospitalization, 13.6% (29/213) of the post-MI AKI patients received hemodialysis. Baseline abnormal creatinine (≥1.5 mg/dL), dyslipidemia, and more advanced KDIGO stages (2 or 3) were associated with an increased risk of requiring in-hospital hemodialysis. Moreover, a more advanced KDIGO stage (≥2) was correlated with higher all-cause in-hospital mortality. <b>Conclusion:</b> AMI patients remain at risk of AKI, which negatively affects their survival in the modern age.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-19T12:05:31.198Z","creation":"2025-04-19T12:05:31.198Z"},"accession":"S-EPMC9604918","cross_references":{"pubmed":["36294404"],"doi":["10.3390/jcm11206083"]}}